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Fattahi, Farnaz-sadat, ZamaniI, Tahereh. (1400). Release of profens from nanofibers: Challenges and opportunities. سامانه مدیریت نشریات علمی, 7(3), 201-218. doi: 10.30476/tips.2021.92124.1108
Farnaz-sadat Fattahi; Tahereh ZamaniI. "Release of profens from nanofibers: Challenges and opportunities". سامانه مدیریت نشریات علمی, 7, 3, 1400, 201-218. doi: 10.30476/tips.2021.92124.1108
Fattahi, Farnaz-sadat, ZamaniI, Tahereh. (1400). 'Release of profens from nanofibers: Challenges and opportunities', سامانه مدیریت نشریات علمی, 7(3), pp. 201-218. doi: 10.30476/tips.2021.92124.1108
Fattahi, Farnaz-sadat, ZamaniI, Tahereh. Release of profens from nanofibers: Challenges and opportunities. سامانه مدیریت نشریات علمی, 1400; 7(3): 201-218. doi: 10.30476/tips.2021.92124.1108

Release of profens from nanofibers: Challenges and opportunities

Trends in Pharmaceutical Sciences
مقاله 7، دوره 7، شماره 3، آذر 2021، صفحه 201-218    اصل مقاله (682.72 K)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.30476/tips.2021.92124.1108
نویسندگان
Farnaz-sadat Fattahi* 1؛ Tahereh ZamaniI2
1Department of Textile Engineering, Isfahan University of Technology, Isfahan, Iran.
2The Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
چکیده
Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanometer measure size with an excessive strength/weight ratio, they are actual suitable as a nanosystem for delivering drug molecules. Drug molecules which mixed in nanofibers, can be released from the surrounding environment by means of various mechanisms in different manners (burst release, sustainable release and tunable release). Nanofibers can be used by way of release rate controlling strategies as proper delivery structures for drug molecules.The objective of this review is to highpoint the capacity of nanofibers as novel releasing substances for profens (Propionic acid derivative drugs including Carprofen; Naproxen; Fenoprofen; Flurbiprofen; Ibuprofen; Ketoprofen and Tiaprofenic acid). The profens are a class of nonselective, nonsteroidal anti-inflammatory drugs (NSAIDs). These drug molecules are derivatives of 2-phenylpropanoic acid. All contain a chiral center resulting in the formation of two enantiomers (R and S) of each profen.
In this review, full information will be reported about the new progresses for release behaviors of profen molecules form the novel nanofibrous delivery systems. The drug releasing kinetics of profen molecules from nanofibers will be described briefly. The authors use more than 80 articles , books and thesis published in the case of nanofibrous profens delivery and releasing systems.
کلیدواژه‌ها
Nanofibers؛ Release characteristic؛ propionic acid derivative drugs؛ kinetic؛ sustainable release
مراجع
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