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Yarahmadi, Pourya, Alirezaei, Mohammad, Forouzannia, Seyed Mohammad, Naser Moghadasi, Abdorreza. (1400). The Outcome of COVID-19 in Patients with a History of Taking Rituximab: A Narrative Review. سامانه مدیریت نشریات علمی, 46(6), 411-419. doi: 10.30476/ijms.2021.88717.1946
Pourya Yarahmadi; Mohammad Alirezaei; Seyed Mohammad Forouzannia; Abdorreza Naser Moghadasi. "The Outcome of COVID-19 in Patients with a History of Taking Rituximab: A Narrative Review". سامانه مدیریت نشریات علمی, 46, 6, 1400, 411-419. doi: 10.30476/ijms.2021.88717.1946
Yarahmadi, Pourya, Alirezaei, Mohammad, Forouzannia, Seyed Mohammad, Naser Moghadasi, Abdorreza. (1400). 'The Outcome of COVID-19 in Patients with a History of Taking Rituximab: A Narrative Review', سامانه مدیریت نشریات علمی, 46(6), pp. 411-419. doi: 10.30476/ijms.2021.88717.1946
Yarahmadi, Pourya, Alirezaei, Mohammad, Forouzannia, Seyed Mohammad, Naser Moghadasi, Abdorreza. The Outcome of COVID-19 in Patients with a History of Taking Rituximab: A Narrative Review. سامانه مدیریت نشریات علمی, 1400; 46(6): 411-419. doi: 10.30476/ijms.2021.88717.1946

The Outcome of COVID-19 in Patients with a History of Taking Rituximab: A Narrative Review

Iranian Journal of Medical Sciences
مقاله 1، دوره 46، شماره 6، بهمن 2021، صفحه 411-419    اصل مقاله (272.49 K)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.30476/ijms.2021.88717.1946
نویسندگان
Pourya Yarahmadi؛ Mohammad Alirezaei؛ Seyed Mohammad Forouzannia؛ Abdorreza Naser Moghadasi*
Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
چکیده
Coronavirus disease 2019 (COVID-19) is a recently emerging disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Notably, the safety of immunosuppressive medications is a major concern during an infectious disease pandemic. Rituximab (RTX), as a monoclonal antibody against CD20 molecule, is widely used for the treatment of various diseases, mostly autoimmune diseases and some malignancies. Previous studies indicated that RTX, as an immunosuppressive medication, may be associated with the increased risk of infections. Moreover, given the wide use of RTX, a necessity of determining the different aspects of RTX use in the COVID-19 era is strongly felt. We reviewed current studies on the clinical courses of patients with SARS-CoV-2 infection. It appears that the use of RTX does not increase morbidity and mortality in most patients. However, underlying diseases and other concomitant medications may play a role in the disease course, while the concerns of vaccine efficacy in patients receiving RTX still need to be addressed. Therefore, more controlled studies are needed for a better conclusion.
کلیدواژه‌ها
Rituximab؛ COVID-19؛ SARS-CoV-2؛ Immune system diseases
سایر فایل های مرتبط با مقاله
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