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Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy | ||
| Iranian Journal of Colorectal Research | ||
| مقاله 7، دوره 9، شماره 2، شهریور 2021، صفحه 78-81 اصل مقاله (1.86 M) | ||
| نوع مقاله: Case Report | ||
| شناسه دیجیتال (DOI): 10.30476/acrr.2021.91296.1100 | ||
| نویسندگان | ||
| Ebrahim Mirakhor* ؛ June Choe؛ Robert I Goodman | ||
| Department of General Internal Medicine, Cedars-Sinai Medical Center | ||
| چکیده | ||
| Introduction: Collagenous Enteritis (CE) is a less common cause of enteropathy presenting with malabsorption as its cardinal symptom. While historically considered a resistant form of celiac disease, newer evidence supports the interaction between genetic predispositions and environmental triggers as the pathophysiologic basis of CE. Case Presentation: Herein we present the case of a 40-year-old woman with two-year history of diarrhea and 32 kg weight loss who was incorrectly diagnosed with celiac disease with refractory symptoms despite adherence to a gluten-free diet. Extensive infectious, inflammatory, secretory, autoimmune workup did not reveal an underlying etiology. Endoscopic evidence of severe villous blunting and biopsy with characteristic patchy enlarged subepithelial collagen layer solidified a diagnosis of CE. Treatment with steroids resulted in resolution of malabsorptive symptoms and gradual weight gain. Conclusion: This case highlights the importance of considering CE in patients presenting with malabsorption especially given significant clinical overlap with other malasbsorptive conditions as well as its therapeutic implications. | ||
| کلیدواژه‌ها | ||
| Collagenous Enteritis؛ Malabsorption؛ Celiac Disease؛ Refractory Diarrhea | ||
| مراجع | ||
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