Seyfi, Doruk, Bui, Chuong, Barto, Walid, Zahid, Assad, Young, Christopher. (1400). FDG PET/CT and Colonoscopy Combine Synergistically in Colorectal Cancer Primary Diagnosis.. سامانه مدیریت نشریات علمی, 9(2), 58-62. doi: 10.30476/acrr.2021.91044.1095
Doruk Seyfi; Chuong Bui; Walid Barto; Assad Zahid; Christopher J Young. "FDG PET/CT and Colonoscopy Combine Synergistically in Colorectal Cancer Primary Diagnosis.". سامانه مدیریت نشریات علمی, 9, 2, 1400, 58-62. doi: 10.30476/acrr.2021.91044.1095
Seyfi, Doruk, Bui, Chuong, Barto, Walid, Zahid, Assad, Young, Christopher. (1400). 'FDG PET/CT and Colonoscopy Combine Synergistically in Colorectal Cancer Primary Diagnosis.', سامانه مدیریت نشریات علمی, 9(2), pp. 58-62. doi: 10.30476/acrr.2021.91044.1095
Seyfi, Doruk, Bui, Chuong, Barto, Walid, Zahid, Assad, Young, Christopher. FDG PET/CT and Colonoscopy Combine Synergistically in Colorectal Cancer Primary Diagnosis.. سامانه مدیریت نشریات علمی, 1400; 9(2): 58-62. doi: 10.30476/acrr.2021.91044.1095

FDG PET/CT and Colonoscopy Combine Synergistically in Colorectal Cancer Primary Diagnosis.

Iranian Journal of Colorectal Research
مقاله 3، دوره 9، شماره 2، شهریور 2021، صفحه 58-62    اصل مقاله (528.22 K)
نوع مقاله: Research/Original Article
شناسه دیجیتال (DOI): 10.30476/acrr.2021.91044.1095
نویسندگان
Doruk Seyfi1؛ Chuong Bui2؛ Walid Barto3؛ Assad Zahid3؛ Christopher J Young* 4
1Department of Colorectal Surgery, Nepean Hospital, Penrith, NSW, Australia
2Department of Nuclear Medicine and PET, Nepean Hospital, Penrith, NSW, Australia
3Department of Colorectal Surgery, Nepean Hospital, Penrith, NSW, Australia.
4The University of Sydney, Central Clinical School, Sydney, New South Wales, Australia
چکیده
Aim: Colonoscopy is the standard for primary colorectal cancer (CRC) detection, but is invasive and imperfect. The aim of this study was to assess the accuracy of 18F-fluorodeoxyglucose (FDG) Positron emission tomography/Computed tomography (PET/CT) and colonoscopy in the diagnosis of primary CRC.
Methods: A retrospective analysis of all patients identified as undergoing a FDG PET/CT scan and a colonoscopy within six months of each other, with no intervening malignancy treatment, over a 12 month period in a single University teaching hospital.
Results: Two hundred and sixty-two patients had FDG PET/CT and colonoscopy within 6 months. 206 were excluded for prior treatment. 56 patients were included, 26 (46%) with confirmed primary CRC tumors and 30 (54%) without. Multivariate logistic regression analysis indicated that CRC diagnosis was more likely when colonoscopy was performed before the FDG PET/CT (Odds Ratio (OR) 21.9 (CI 2.6-183) and when CRC was diagnosed on FDG PET/CT (OR 12.3 (CI 3.0-51.0). The ROC-AUC for FDG PET/CT and colonoscopy was 0.81 (CI 0.70-0.93, p <0.001) and 0.96 (CI 0.90-1.0, p <0.001) respectively.
Conclusions: Colonoscopy is very good and FDG PET/CT is good as diagnostic tests for CRC primary diagnosis. Together they facilitated diagnosis in all CRC primaries. PET/CT should be considered in patients’ with incomplete colonoscopy where there is suspicion for CRC primary.
کلیدواژه‌ها
18F-fluorodeoxyglucose؛ Positron emission tomography؛ Computed tomography؛ Colonoscopy؛ Colorectal Cancer
مراجع
آمار
تعداد مشاهده مقاله: 1,289
تعداد دریافت فایل اصل مقاله: 691