LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,149
تعداد مقالات10,518
تعداد مشاهده مقاله45,419,841
تعداد دریافت فایل اصل مقاله11,296,177
Ahmadzadeh, Saleheh, Gholami, Mandana, Soheili, Shahram, Ghazalian, Farshad. (1400). The Effect of Eight Weeks Aerobic Training and Omega3 Ingestion on the Levels of Adipsin and Insulin Resistance in Overweight and Obese Women. سامانه مدیریت نشریات علمی, 8(3), 134-141. doi: 10.30476/whb.2021.89493.1096
Saleheh Ahmadzadeh; Mandana Gholami; Shahram Soheili; Farshad Ghazalian. "The Effect of Eight Weeks Aerobic Training and Omega3 Ingestion on the Levels of Adipsin and Insulin Resistance in Overweight and Obese Women". سامانه مدیریت نشریات علمی, 8, 3, 1400, 134-141. doi: 10.30476/whb.2021.89493.1096
Ahmadzadeh, Saleheh, Gholami, Mandana, Soheili, Shahram, Ghazalian, Farshad. (1400). 'The Effect of Eight Weeks Aerobic Training and Omega3 Ingestion on the Levels of Adipsin and Insulin Resistance in Overweight and Obese Women', سامانه مدیریت نشریات علمی, 8(3), pp. 134-141. doi: 10.30476/whb.2021.89493.1096
Ahmadzadeh, Saleheh, Gholami, Mandana, Soheili, Shahram, Ghazalian, Farshad. The Effect of Eight Weeks Aerobic Training and Omega3 Ingestion on the Levels of Adipsin and Insulin Resistance in Overweight and Obese Women. سامانه مدیریت نشریات علمی, 1400; 8(3): 134-141. doi: 10.30476/whb.2021.89493.1096

The Effect of Eight Weeks Aerobic Training and Omega3 Ingestion on the Levels of Adipsin and Insulin Resistance in Overweight and Obese Women

Women’s Health Bulletin
مقاله 2، دوره 8، شماره 3 - شماره پیاپی 30، مهر 2021، صفحه 134-141    اصل مقاله (225.81 K)
نوع مقاله: Research Article
شناسه دیجیتال (DOI): 10.30476/whb.2021.89493.1096
نویسندگان
Saleheh Ahmadzadeh1؛ Mandana Gholami* 1؛ Shahram Soheili2؛ Farshad Ghazalian1
1Department of Physical Education and Sport Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
2Department of Physical Education and Sport Sciences, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
چکیده
Background: Exercise training and omega-3 supplementation are believed to have a positive effect on obese and overweight people. We conducted the present study in order to investigate the effect of aerobic training and omega3 ingestion on the levels of Adipsin and insulin resistance in overweight and obese women.
Methods: In this semi-experimental study conducted in Tehran, summer 2020, 40 overweight and obese women (aged from 20 to 35 years old, and BMI 29.6±1.93 kg.m2) were assigned in four equal groups, namely placebo (P), omega-3 (O), training (E), and training+omega-3 (OE) groups. The subjects in the training and training+omega-3 groups completed the eight-week (three sessions per week) aerobic training program. 2000 mg omega-3 supplement was consumed on a daily basis. Blood samples were obtained before and after completing the intervention and Adipsin and insulin levels were measured. The data were analyzed via repeated measures analysis of variance (ANOVA) test along with Tukey post-hoc test. The study was approved under the IRCT registration code of IRCT20200811048360N1.
Results: The findings of the present research shed light on a significant decrease in serum Adipsin levels in the E and OE groups compared to those in the P and O groups (p <0.05). Moreover, insulin resistance significantly decreased in E compared with that in the P group (P=0.012) and also in the OE group compared to that in the P (P=0.001) and O (P=0.009) groups.
Conclusion: The present study indicated that omega-3 supplementation could increase the effect of exercise training on the reduction in the Adipsin and insulin resistance; further effects may be observed by increasing the duration of exercise training period.
کلیدواژه‌ها
Obesity؛ Endurance training؛ Adipokines؛ Complement factor D
مراجع
1. Derosa G, Fogari E, D’Angelo A, Bianchi L, Bonaventura A, Romano D, Maffioli P. Adipocytokine levels in obese and non-obese subjects: an observational study. Inflammation. 2013;36(4):914-20. doi: 10.1007/s10753-013-9620-4. PubMed PMID: 23467997. ## 2. Flier JS. Obesity wars: molecular progress confronts an expanding epidemic. Cell. 2004;116(2):337-50. doi: 10.1016/s0092-8674(03)01081-x. PubMed PMID: 14744442. ## 3. Fain JN, Madan AK, Hiler ML, Cheema P, Bahouth SW. Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans. Endocrinology. 2004;145(5):2273-82. doi: 10.1210/en.2003-1336. PubMed PMID: 14726444. ## 4. Lo JC, Ljubicic S, Leibiger B, Kern M, Leibiger IB, Moede T, et al. Adipsin is an adipokine that improves β cell function in diabetes. Cell. 2014;158(1):41-53. doi: 10.1016/j.cell.2014.06.005. PubMed PMID: 24995977; PubMed Central PMCID: PMC4128197. ## 5. Cook KS, Min HY, Johnson D, Chaplinsky RJ, Flier JS, Hunt CR, et al. Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve. Science. 1987;237(4813):402-5. doi: 10.1126/science.3299705. PubMed PMID: 3299705. ## 6. Flier JS, Cook KS, Usher P, Spiegelman BM. Severely impaired adipsin expression in genetic and acquired obesity. Science. 1987; 237(4813):405-8. doi: 10.1126/science.3299706. PubMed PMID: 3299706. ## 7. Wang JS, Lee WJ, Lee IT, Lin SY, Lee WL, Liang KW, et al. Association between serum Adipsin levels and insulin resistance in subjects with various degrees of glucose intolerance. J Endocr Soc. 2019;3(2):403-410. doi: 10.1210/js.2018-00359. PubMed PMID: 30746502; PubMed Central PMCID: PMC6364621. ## 8. Karajibani M, Montazerifar F, Sadeghi MB, Keikhaie MA, Dashipour A. Serum Fetuin-A and Adipsin Levels in Type II Diabetes Patients. Int J High Risk Behav Addict. 2019;8(3):e91963. doi: 10.5812/ijhrba.91963. ## 9. Chedraui P, Pérez-López FR, Escobar GS, Palla G, Montt-Guevara M, Cecchi E, et al. Circulating leptin, resistin, adiponectin, visfatin, adipsin and ghrelin levels and insulin resistance in postmenopausal women with and without the metabolic syndrome. Maturitas. 2014;79(1):86-90. doi: 10.1016/j.maturitas.2014.06.008. PubMed PMID: 25015014. ## 10. Naderi L, Sharifi G. Comparison of the Effect of 8 weeks Concurrent Training and Green Coffee Supplementation on Serum Adipsin and Insulin Resistance in Obese Women. Armaghane danesh. 2017;22(5):623-636. Persian. ## 11. Azizi M, Tadibi V, Behpour N. The effect of aerobic exercise training on β-cell function and circulating levels of adipsin in community of obese women with type 2 diabetes mellitus. International Journal of Diabetes in Developing Countries. 2017;37(3):298-304. doi: 10.1007/s13410-016-0504-7. ## 12. Buckley JD, Howe PRC. Anti‐obesity effects of long‐chain omega‐3 polyunsaturated fatty acids. Obes Rev. 2009;10(6):648-59. doi: 10.1111/j.1467-789X.2009.00584.x. PubMed PMID: 19460115. ## 13. Chow S-C, Shao J, Wang H, Lokhnygina Y. Sample size calculations in clinical research. CRC press; 2017. ## 14. Sheibani S, Hanachi P, Refahiat MA. Effect of Aerobic Exercise on Serum Concentration of Apelin, TNFα and Insulin in Obese Women. Iran J Basic Med Sci. 2012;15(6):1196-201. PubMed PMID: 23653851; PubMed Central PMCID: PMC3646232. ## 15. Dadash Nejad F, Gholami M, Soheili S. The effect of eight-week combined exercise training (resistance-endurance) and Omega-3 ingestion on the levels of fetuin-A and metabolic profile in obese elderly women. Daneshvar Medicine. 2020;27(4):35-44. ## 16. Yap BW, Sim CH. Comparisons of various types of normality tests. Journal of Statistical Computation and Simulation. 2011;81(12):2141-2155. doi: 10.1080/00949655.2010.520163. ## 17. Blüher M. Clinical relevance of adipokines. Diabetes Metab J. 2012;36(5):317-27. doi: 10.4093/dmj.2012.36.5.317. PubMed PMID: 23130315; PubMed Central PMCID: PMC3486977. ## 18. Maury E, Brichard SM. Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome. Mol Cell Endocrinol. 2010;314(1):1-6. doi: 10.1016/j.mce.2009.07.031. PubMed PMID: 19682539. ## 19. Tafere GG, Wondafrash DZ, Zewdie KA, Assefa BT, Ayza MA. Plasma Adipsin as a Biomarker and Its Implication in Type 2 Diabetes Mellitus. Diabetes Metab Syndr Obes. 2020; 13:1855-1861. doi: 10.2147/DMSO.S253967. PubMed PMID: 32547147; PubMed Central PMCID: PMC7264027. ## 20. Vasilenko MA, Kirienkova EV, Skuratovskaia DA, Zatolokin PA, Mironyuk NI, Litvinova LS. The role of production of adipsin and leptin in the development of insulin resistance in patients with abdominal obesity. Dokl Biochem Biophys. 2017;475(1):271-276. doi: 10.1134/S160767291704010X. PubMed PMID: 28864895. ## 21. Li Y, Zou W, Brestoff JR, Rohatgi N, Wu X, Atkinson JP, et al. Fat-Produced Adipsin Regulates Inflammatory Arthritis. Cell Rep. 2019;27(10):2809-2816. doi: 10.1016/j.celrep.2019.05.032. PubMed PMID: 31167128; PubMed Central PMCID: PMC6643993. ## 22. Mohammadi Javid N, Behpoor N, Taedibi V. Home Based Aerobic Training and the Changes in Adipsin Levels and Visceral Adiposity Index (VAI) in Women with Polycystic Ovary Syndrome. 2020; Int J Health Life Sci. 2020;6(2): e97400. doi: 10.5812/ijhls.97400. ## 23. Ortega JF, Morales‐Palomo F, Fernandez‐Elias V, Hamouti N, Bernardo FJ, Martin‐Doimeadios RC, et al. Dietary supplementation with omega‐3 fatty acids and oleate enhances exercise training effects in patients with metabolic syndrome. Obesity. 2016;24(8):1704-11. doi: 10.1002/oby.21552. PubMed PMID: 27356240. ## 24. Hawley JA, Lessard SJ. Exercise training‐induced improvements in insulin action. Acta Physiol. 2008;192(1):127-35. doi: 10.1111/j.1748-1716.2007.01783. x. PubMed PMID: 18171435. ##

آمار
تعداد مشاهده مقاله: 523
تعداد دریافت فایل اصل مقاله: 389


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب