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Farazestanian, Marjaneh, Hassanzadeh, Maliheh, Yousefi, Zohreh, Homaee, Fatemeh, Saghafi, Nafiseh, Jafarian, Amir Hossein, Layegh, Parvaneh, Mottaghi, Mansoureh, Shirinzadeh, Laya, Mousavi Seresht, Leila, Azimi, Helena. (1400). Pregnancy Before Completion of Follow-Up in Gestational Trophoblastic Neoplasia: a Case Report. سامانه مدیریت نشریات علمی, 8(3), 189-194. doi: 10.30476/whb.2021.90959.1118
Marjaneh Farazestanian; Maliheh Hassanzadeh; Zohreh Yousefi; Fatemeh Homaee; Nafiseh Saghafi; Amir Hossein Jafarian; Parvaneh Layegh; Mansoureh Mottaghi; Laya Shirinzadeh; Leila Mousavi Seresht; Helena Azimi. "Pregnancy Before Completion of Follow-Up in Gestational Trophoblastic Neoplasia: a Case Report". سامانه مدیریت نشریات علمی, 8, 3, 1400, 189-194. doi: 10.30476/whb.2021.90959.1118
Farazestanian, Marjaneh, Hassanzadeh, Maliheh, Yousefi, Zohreh, Homaee, Fatemeh, Saghafi, Nafiseh, Jafarian, Amir Hossein, Layegh, Parvaneh, Mottaghi, Mansoureh, Shirinzadeh, Laya, Mousavi Seresht, Leila, Azimi, Helena. (1400). 'Pregnancy Before Completion of Follow-Up in Gestational Trophoblastic Neoplasia: a Case Report', سامانه مدیریت نشریات علمی, 8(3), pp. 189-194. doi: 10.30476/whb.2021.90959.1118
Farazestanian, Marjaneh, Hassanzadeh, Maliheh, Yousefi, Zohreh, Homaee, Fatemeh, Saghafi, Nafiseh, Jafarian, Amir Hossein, Layegh, Parvaneh, Mottaghi, Mansoureh, Shirinzadeh, Laya, Mousavi Seresht, Leila, Azimi, Helena. Pregnancy Before Completion of Follow-Up in Gestational Trophoblastic Neoplasia: a Case Report. سامانه مدیریت نشریات علمی, 1400; 8(3): 189-194. doi: 10.30476/whb.2021.90959.1118

Pregnancy Before Completion of Follow-Up in Gestational Trophoblastic Neoplasia: a Case Report

Women’s Health Bulletin
مقاله 8، دوره 8، شماره 3 - شماره پیاپی 30، مهر 2021، صفحه 189-194    اصل مقاله (650.11 K)
نوع مقاله: Case Report
شناسه دیجیتال (DOI): 10.30476/whb.2021.90959.1118
نویسندگان
Marjaneh Farazestanian1؛ Maliheh Hassanzadeh1؛ Zohreh Yousefi1؛ Fatemeh Homaee2؛ Nafiseh Saghafi3؛ Amir Hossein Jafarian4؛ Parvaneh Layegh5؛ Mansoureh Mottaghi6؛ Laya Shirinzadeh6؛ Leila Mousavi Seresht7؛ Helena Azimi* 1
1Department of Obstetrics and Gynecology, Fellowship of Gynecology Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2Department of of Radiotherapy, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
5Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
6Fellowship of Gynecology Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
7Department of Obstetrics and Gynecology, Fellowship of Gynecology Oncology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده
Introduction: Choriocarcinoma is a rare and malignant tumor, which may present during or following any type of pregnancy. This tumor often demonstrates rapid hematogenous spread to multiple organs and is associated with high levels of human chorionic gonadotropin (HCG) and a good response to chemotherapy. Herein, we introduced a case of metastatic choriocarcinoma who failed to response to conventional therapies.
Case presentation: A 22-year-old woman referred with vaginal bleeding. The evaluations revealed that she had a metastatic choriocarcinoma that failed to response to conventional therapies. Continuation of chemotherapy was not possible due to the development of neutropenia. Interestingly, the patient achieved a complete remission spontaneously without receiving further treatment. During the follow-up period, when the patient should not become pregnant, she became pregnant and had no problems during the pregnancy.
Conclusions: Gestational trophoblastic neoplasia is a rare disease. The majority of women suffering from this disease can be cured and their reproductive function could be preserved through the utilization of sensitive quantitation assay for human chorionic gonadotropin (β-hCG) and highly effective chemotherapy.
کلیدواژه‌ها
Choriocarcinoma؛ Metastasis؛ Chemotherapy
مراجع
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