پیوندهای مفید
آمار
| تعداد نشریات | 20 |
| تعداد شماره‌ها | 1,149 |
| تعداد مقالات | 10,518 |
| تعداد مشاهده مقاله | 45,415,514 |
| تعداد دریافت فایل اصل مقاله | 11,291,309 |
Dosimetric Evaluation of 4 Field Three-Dimensional Conformal Radiation Therapy and 7 Field Intensity Modulated Radiation Therapy in Esophageal Cancer Treated with Definitive Chemoradiation | ||
| Middle East Journal of Cancer | ||
| مقاله 15، دوره 13، شماره 1 - شماره پیاپی 49، فروردین 2022، صفحه 135-142 اصل مقاله (976.03 K) | ||
| نوع مقاله: Original Article(s) | ||
| شناسه دیجیتال (DOI): 10.30476/mejc.2021.85492.1285 | ||
| نویسندگان | ||
| Chintamani Hanumantarao Sridhar1؛ Mariappan Senthiappan Athiyamaan* 2 | ||
| 1Medical Physicist/RSO, Department of Radiation Oncology, Father Muller Medical College, Kankanady, Mangalore, India | ||
| 2Department of Radiation Oncology, Father Muller Medical College, Kankanady, Mangalore, India | ||
| چکیده | ||
| Background: The present study aimed to evaluate dosimetrically and correlate the lung and heart dose volume histogram (DVH) of the 4 field three-dimensional conformal radiotherapy (3DCRT) with 7 field intensity modulated radiotherapy (IMRT) in patients with oesophageal cancers. Method: This retrospective dosimetric study considered 20 oesophagus cancer patients treated with definitive chemoradiation with IMRT technique. In the 7 field IMRT technique, the first phase delivered a dose of 36Gy/18fr followed by 18Gy/9fr in two weeks in the second phase. In the 3DCRT technique, the first phase was planned with 4 field technique with two parallel opposed and two posterior oblique fields, followed by the 3 field technique in the second phase. The assessments of the techniques were performed using differential DVH analysis of the right and left lungs, heart, and the spinal cord. The values of the mean dose, V20 (volume receiving 20 Gy), and V30 (volume receiving 30 Gy) were assessed for any correlations. Results: The DVH of V20 in IMRT showed 5% less lung volume irradiation compared with the 3DCRT plans and over 20% less V30 for irradiated heart volume. The study demonstrated a statistical advantage of using 7 field IMRT over 4 field 3DCRT in reducing the mean percentage dose to both lungs, heart, and spinal cord. Conclusion: 7 field IMRT is superior to 4 field 3DCRT plans in significantly reducing the average percentage of irradiated volume of both the lung and heart in esophageal cancer radiation therapy. | ||
| کلیدواژه‌ها | ||
| Esophageal neoplasms؛ Radiotherapy؛ Conformal؛ Intensity-modulated؛ Radiation dosimetry؛ Heart | ||
| اصل مقاله | ||
|
How to cite this article: Sridhar CH, Athiyamaan MS. Dosimetric evaluation of 4 field three-dimensional conformal radiation therapy and 7 field intensity modulated radiation therapy in esophageal cancer treated with definitive chemoradiation. Middle East J Cancer. 2022;13(1):135-42. doi: 10.30476/mejc.2021.85492.1285. | ||
| مراجع | ||
|
1.Stewart BW, Wild CP. World Cancer Report 2014. WHO Press; 2014. P. Wild ISBN: 978-92-832-0429-9. 2.Domper Arnal MJ, Ferrández Arenas Á, Lanas Arbeloa Á. Esophageal cancer: Risk factors, screening and endoscopic treatment in Western and Eastern countries. World J Gastroenterol. 2015;21(26):7933-43. doi: 10.3748/wjg.v21.i26.7933. 3.Pennathur A, Gibson MK, Jobe BA, Luketich JD. Oesophageal carcinoma. Lancet. 2013;381(9864):400-12. doi: 10.1016/S0140-6736(12)60643-6. 4.Liang H, Fan JH, Qiao YL. Epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China. Cancer Biol Med. 2017;14(1):33-41. doi: 10.20892/j.issn.2095-3941.2016.0093. 5. Bosset J, Gignoux M, Triboulet J, Tiret E, Mantion G, Elias D, et.al. Chemoradiotherapy followed by surgery compared with surgery alone in squamous cell cancer of the esophagus. N Engl J Med. 1997;337:161-7. doi: 10.1056/NEJM19970717370304. 6.Cooper J, Guo M, Herskovic A, Macdonald JS, Martenson JA Jr, Al-Sarraf M, et al. Chemoradiotherapy of locally advanced esophageal cancer: Long-term follow-up of a prospective randomized trial (RTOG 85-01). J Am Med Assoc. 1999;281:1623-7. doi: 10.1001/jama.281.17.1623. 7.Minsky BD, Pajak T, Ginsberg R, Pisansky TM, Martenson J, Komaki R, et al. INT 0123 (Radiation Therapy Oncology Group 94-05) phase III trial of combinedmodality therapy for esophageal cancer: High-dose versus standard-dose radiation therapy. J Clin Oncol. 2002;20(5):1167-74.doi: 10.1200/JCO. 2002.20.5.1167. 8. Hu X, He W, Wen S, Feng X, Fu X, Liu Y, et al. Is IMRT superior or inferior to 3DCRT in radiotherapy for NSCLC? A meta-analysis. PLoS One. 2016;11(4):e0151988. doi: 10.1371/journal.pone. 0151988. 9. Kole TP, Aghayere O, Kwah J, Yorke ED, Goodman KA. Comparison of heart and coronary artery doses associated with intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy for distal esophageal cancer. Int J Radiat Oncol Biol Phys. 2012;83(5):1580-6. doi: 10.1016/j.ijrobp.2011.10.053. 10. Bedford JL, Viviers L, Guzel Z, Child PJ, Webb S, Tait DM. A quantitative treatment planning study evaluating the potential of dose escalation in conformal radiotherapy of the oesophagus. Radiother Oncol. 2000;57(2):183-93. doi: 10.1016/s0167-8140(00) 00258-9. 11.Ling TC, Slater JM, Nookala P, Mifflin R, Grove R, Ly AM, et al. Analysis of intensity-modulated radiation therapy (IMRT), proton and 3D conformal radiotherapy (3D-CRT) for reducing perioperative cardiopulmonary complications in esophageal cancer patients. Cancers (Basel). 2014;6(4):2356-68. doi: 10.3390/cancers 6042356. 12.Ghosh S, Kapoor R, Gupta R, Kholsa, D, Kochhar R, Oinam AS, et al. An evaluation of three dimensional conformal radiation therapy versus intensity modulated radiation therapy in radical chemoradiation of esophageal cancer: a dosimetric study. Clin Cancer Invest J. 2012;1:65-70. doi: 10.4103/2278-0513.99565. 13.Lee H, Vaporciyan A, Cox J, Tucker SL, Putnam JB Jr, Ajani JA, et al. Postoperative pulmonary complications after preoperative chemoradiation for esophageal carcinoma: Correlation with pulmonary dose-volume histogram parameters. Int J Radiat Oncol Biol Phys. 2003;57(5):1317-22. doi: 10.1016/s0360-3016(03)01373-7. 14.Khoo VS, Oldham M, Adams EJ, Bedford JL, Webb S, Brada M. Comparison of intensity- modulated tomotherapy with stereotactically guided conformal radiotherapy for brain tumors. Int J Radiat Oncol Biol Phys. 1999;45(2):415-25. doi: 10.1016/s0360-3016(99)00213-8. 15.Fenkell L, Kaminsky I, Breen S, Huang S, Van Prooijen M, Ringash J. Dosimetric comparison of IMRT vs. 3D conformal radiotherapy in the treatment of cancer of the cervical esophagus. Radiother Oncol. 2009;89(3):287-91. doi: 10.1016/j.radonc.2008.08.008. 16.Xu D, Li G, Li H, Jia F. Comparison of IMRT versus 3D-CRT in the treatment of esophagus cancer: A systematic review and meta-analysis. Medicine (Baltimore). 2017;96(31):e7685. doi: 10.1097/MD.00 00000000007685. 17. Chandra A, Guerrero TM, Liu HH, Tucker SL, Liao Z, Wang X, et al. Feasibility of using intensity- modulated radiotherapy to improve lung sparing in treatment planning for distal esophageal cancer. Radiother Oncol. 2005;77(3):247-53. doi: 10.1016/j. radonc.2005.10.017. 18. Wu VW, Kwong DL, Sham JS. Target dose conformity in 3-dimensional conformal radiotherapy and intensity modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2004;71(2):201-6. doi: 10.1016/j.radonc.2004.03.004. | ||
|
آمار تعداد مشاهده مقاله: 2,482 تعداد دریافت فایل اصل مقاله: 3,036 |
||