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Azmoodeh, Shahin, Soleimani, Esmaeil, Issazadegan, Ali. (1400). The Effects of Transcranial Direct Current Stimulation on Depression, Anxiety, and Stress in Patients with Epilepsy: A Randomized Clinical Trial. سامانه مدیریت نشریات علمی, 46(4), 272-280. doi: 10.30476/ijms.2020.83233.1215
Shahin Azmoodeh; Esmaeil Soleimani; Ali Issazadegan. "The Effects of Transcranial Direct Current Stimulation on Depression, Anxiety, and Stress in Patients with Epilepsy: A Randomized Clinical Trial". سامانه مدیریت نشریات علمی, 46, 4, 1400, 272-280. doi: 10.30476/ijms.2020.83233.1215
Azmoodeh, Shahin, Soleimani, Esmaeil, Issazadegan, Ali. (1400). 'The Effects of Transcranial Direct Current Stimulation on Depression, Anxiety, and Stress in Patients with Epilepsy: A Randomized Clinical Trial', سامانه مدیریت نشریات علمی, 46(4), pp. 272-280. doi: 10.30476/ijms.2020.83233.1215
Azmoodeh, Shahin, Soleimani, Esmaeil, Issazadegan, Ali. The Effects of Transcranial Direct Current Stimulation on Depression, Anxiety, and Stress in Patients with Epilepsy: A Randomized Clinical Trial. سامانه مدیریت نشریات علمی, 1400; 46(4): 272-280. doi: 10.30476/ijms.2020.83233.1215

The Effects of Transcranial Direct Current Stimulation on Depression, Anxiety, and Stress in Patients with Epilepsy: A Randomized Clinical Trial

Iranian Journal of Medical Sciences
مقاله 5، دوره 46، شماره 4، مهر 2021، صفحه 272-280    اصل مقاله (333.3 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2020.83233.1215
نویسندگان
Shahin Azmoodeh؛ Esmaeil Soleimani* ؛ Ali Issazadegan
Department of Psychology, School of Literature and Humanities, Urmia University, Urmia, Iran
چکیده
Background: Epilepsy is a chronic disorder that affects both sexes and causes some physiological and psychological disabilities. The present study aimed to examine the effects of transcranial direct current stimulation (tDCS) on the psychological profile of patients with epilepsy.
Methods: The design of the present study was a randomized clinical trial with a pretest-posttest and a control group. The statistical population comprised patients with epilepsy, who were referred for treatment to a private health center in Urmia in 2019. The sample consisted of 30 patients with epilepsy selected via the convenience sampling method. Data collection was performed through the use of the Depression, Anxiety, and Stress Scale-21 (DASS-21) questionnaire. After the pretest, 15 subjects were randomly assigned to the intervention group, and 15 subjects were placed in the control group. The intervention was performed in 10 sessions, and the duration of stimulation was 20 minutes. The anode was placed in the F3 region (left hemisphere), the cathode in the F4 (right hemisphere), and the current intensity was 1.5 mA. After the intervention, the posttest was conducted for both groups, and the data were analyzed using a univariate covariance analysis in the SPSS software, version 23. A P value of less than 0.05 was considered statistically significant.
Results: The results of the ANCOVA analyses revealed significant differences between the intervention and control groups. The tDCS group represented a significant decrease in the scales of depression, anxiety, and stress in the posttest in comparison with the pretest (P≤0.001).
Conclusion: The results showed that tDCS could reduce depression, anxiety, and stress with the changes caused in the brain system.
Trial Registration Number: IRCT20190803044417N1.
کلیدواژه‌ها
Anxiety؛ Epilepsy؛ Depression؛ Transcranial direct current stimulation
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