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Palliative Radiotherapy to Asymptomatic Bone Metastasis: Is It Beneficial or Not? Single Institution Experience | ||
| Middle East Journal of Cancer | ||
| مقاله 13، دوره 12، شماره 3 - شماره پیاپی 47، مهر 2021، صفحه 422-428 اصل مقاله (624.66 K) | ||
| نوع مقاله: Original Article(s) | ||
| شناسه دیجیتال (DOI): 10.30476/mejc.2021.84106.1201 | ||
| نویسندگان | ||
| Shoukri Hassan Elazab؛ Hend M. Hamdey Rashed Elkalla* ؛ Mohamed S. Zahi | ||
| Department of Clinical Oncology and Nuclear Medicine, Faculty of medicine, Mansoura University, Mansoura, Egypt | ||
| چکیده | ||
| Background: Bone metastases are believed to be the complications of cancer occurring in 20-75% of patients with advanced tumors. External beam radiation therapy (EBRT) is recommended in case of symptomatic bone metastases. Preventing skeletal-related events (SREs) and pain through early treatment of bone metastases is to be studied. We conducted the present study to investigate EBRT in asymptomatic bone metastases. Method: A retrospective cohort study for patients with bone metastases without symptoms, who were treated with EBRT, formed group A. Group B comprised the patients who did not receive EBRT. The time from diagnosis to onset of the 1st SRE was recorded for both groups. The follow-up period was three years. Pain was moderate to severe when rated as 5/10. Results: Asymptomatic bone metastases were found in 200 patients. They were free from pain or pathological fractures. They were divided into two groups of A and B. The overall demographics and disease characteristics were well-balanced for the two groups. The two groups were more or less similar concerning the mean age and sex, with no statistically significant differences; the mean age in groups A and B was 57 years. For both groups, the mean time from the occurrence of asymptomatic bony metastases to the onset of SRE were about 33 and 19 months for groups A and B, respectively, which is statistically significant. Conclusion: Prophylactic EBRT of metastatic breast and prostate cancer patients should be considered in order to delay the onset of SREs and improve the quality of life. | ||
| کلیدواژه‌ها | ||
| Palliative radiotherapy؛ SREs؛ Bone metastasis؛ Bisphosphonates | ||
| اصل مقاله | ||
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How to cite this article: Elazab SH, Elkalla HMHR, Zahi MS. Palliative radiotherapy to asymptomatic bone metastasis: Is it beneficial or not? Single institution experience. Middle East J Cancer. 2021;12(3):422- 8. doi: 10.30476/mejc.2021.84106.1201. | ||
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