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The Effect of Argan Oil on Surrogate Markers in Cardiovascular Diseases: A Systematic Review and Meta-Analysis | ||
| International Journal of Nutrition Sciences | ||
| مقاله 2، دوره 5، شماره 4، اسفند 2020، صفحه 159-166 اصل مقاله (1.08 M) | ||
| نوع مقاله: Review Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijns.2020.87532.1083 | ||
| نویسندگان | ||
| Maryam Ghaseminasab Parizi1؛ Mohammad Hassan Eftekhari* 1؛ Sayedeh Maryam Tabibzadeh2؛ Maryam Shafiee3؛ Seyed Mohammad Mazloomi4 | ||
| 1Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 2Anesthesia and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 3Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 4Nutrition Research Center, Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| چکیده | ||
| Background: Argan oil is a natural vegetable oil recently received much attention because of ingredients such as tocopherols, particularly in its γ-isoform, polyphenols, and phytosterols which are rich sources of antioxidants with therapeutic effects on cardiovascular diseases, diabetes, obesity, hypercholesterolemia, hypertension, hepatic disease, cancer, acne, sebum, and aging. One half tablespoon per day was shown to be effective to prevent metabolic diseases. Methods: The current systematic review and meta-analysis evaluated the effect of argan oil on cardiovascular health. PubMed, Scopus, EMBASE, and Web of Science databases were searched from their beginning to August 2019. All clinical trials studied the effect of argan oil on the systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), vitamin E, apolipoprotein A (Apo A) and apolipoprotein B (Apo B) levels for at least two weeks were included. Five studies underwent metaanalysis techniques using random-effects models. Results: Collective outcomes showed that argan oil increased the vitamin E level (SMD: 2.98, 95%CI: -0.51, 6.48, p =0.09) non-signifcantly compared with control group. Argan oil could signifcantly raise the Apo A level (SMD: 0.74, 95%CI: 0.39, 1.10, p <0.001), and decrease the Apo B level signifcantly (SMD: -0.58, 95%CI: -0.93, -0.23, p =0.001). Conclusion: Our study showed that consumption of argan oil increased Apo-A and vitamin E levels, but further clinical studies on a larger number of patients are needed to explain and confrm the biological and clinical effects of argan oil. | ||
| کلیدواژه‌ها | ||
| Argan oil؛ Apolipoproteins؛ Surrogate markers؛ Cardiovascular diseases؛ Vitamin E | ||
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آمار تعداد مشاهده مقاله: 2,471 تعداد دریافت فایل اصل مقاله: 1,618 |
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