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Mosalaei, Ahmad, Rajaei, Majdaddin, Nasrollahi, Hamid, Hamedi, Seyed Hassan, Omidvari, Shapour, Ahmadloo, Niloofar, Ansari, Mansour, Mohammadianpanah, Mohammad. (1400). A Comparison of Early Side-Effects of Short-Course and Long-Course Radiotherapy in Rectal Cancer. سامانه مدیریت نشریات علمی, 12(2), 255-260. doi: 10.30476/mejc.2020.83111.1133
Ahmad Mosalaei; Majdaddin Rajaei; Hamid Nasrollahi; Seyed Hassan Hamedi; Shapour Omidvari; Niloofar Ahmadloo; Mansour Ansari; Mohammad Mohammadianpanah. "A Comparison of Early Side-Effects of Short-Course and Long-Course Radiotherapy in Rectal Cancer". سامانه مدیریت نشریات علمی, 12, 2, 1400, 255-260. doi: 10.30476/mejc.2020.83111.1133
Mosalaei, Ahmad, Rajaei, Majdaddin, Nasrollahi, Hamid, Hamedi, Seyed Hassan, Omidvari, Shapour, Ahmadloo, Niloofar, Ansari, Mansour, Mohammadianpanah, Mohammad. (1400). 'A Comparison of Early Side-Effects of Short-Course and Long-Course Radiotherapy in Rectal Cancer', سامانه مدیریت نشریات علمی, 12(2), pp. 255-260. doi: 10.30476/mejc.2020.83111.1133
Mosalaei, Ahmad, Rajaei, Majdaddin, Nasrollahi, Hamid, Hamedi, Seyed Hassan, Omidvari, Shapour, Ahmadloo, Niloofar, Ansari, Mansour, Mohammadianpanah, Mohammad. A Comparison of Early Side-Effects of Short-Course and Long-Course Radiotherapy in Rectal Cancer. سامانه مدیریت نشریات علمی, 1400; 12(2): 255-260. doi: 10.30476/mejc.2020.83111.1133

A Comparison of Early Side-Effects of Short-Course and Long-Course Radiotherapy in Rectal Cancer

Middle East Journal of Cancer
مقاله 11، دوره 12، شماره 2 - شماره پیاپی 46، تیر 2021، صفحه 255-260    اصل مقاله (120.12 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2020.83111.1133
نویسندگان
Ahmad Mosalaei1؛ Majdaddin Rajaei2؛ Hamid Nasrollahi* 1؛ Seyed Hassan Hamedi2؛ Shapour Omidvari3؛ Niloofar Ahmadloo2؛ Mansour Ansari3؛ Mohammad Mohammadianpanah4
1Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
2Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
3Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: The variety of neoadjuvant treatments concerning rectal cancer has led to acute complications. The present study aimed to evaluate and compare the acute complications of short-course (SC) and long-course (LC) radiotherapy.
Method: We studied 100 patients suffering from rectal cancer, who referred to Nemazee Hospital before their surgery, in this cross-sectional study. The patients were divided into two categories: SC (25 grays radiotherapy at 5 fractions in 5 days) and LC (chemoradiotherapy with a dose of 45-50.4 grays in 25- 28 fraction in 5-6 weeks with concurrent Capecitabine (825 mg / m2) twice daily and five days a week). Subsequently, we evaluated them for acute complications in the SC group 10-14 days after the end of the treatment and in the LC group at intervals of the treatment, the end of it and 2 weeks afterwards.
Results: In the LC group compared to the SC group, the percentage of patients with grade 1 diarrhea, grade 2 colitis and grade 1 cystitis at the end of the treatment was statistically different (p <0.001, P=0.046, P=0.036 ). In addition, the total number of the patients with grade 1 and 2 dermatitis was higher in the LC group compared with that in the SC group (P=0.046). We observed no significant differences between the two groups concerning the severe acute complications (P>0.05).
Conclusion: This study implied that there were no significant differences regarding severe acute complication between the two groups.
کلیدواژه‌ها
Radiotherapy؛ Rectal nesoplasms؛ Side-effects
اصل مقاله

How to cite this article:

Mosalaei A, Rajaei M, Nasrollahi H, Hamedi S, Omidvari S, Ahmadloo N, et al. A comparison of early side-effects of short course and long course radiotherapy in rectal cancer. Middle East J Cancer. 2021;12(2): 255-60. doi: 10.30476/mejc.2020.83111.1133.

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