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Acute Renal Failure: A Rare Initial Presentation of Acute Lymphoblastic Leukemia | ||
Middle East Journal of Cancer | ||
مقاله 29، دوره 11، شماره 4 - شماره پیاپی 44، دی 2020، صفحه 512-515 اصل مقاله (2.24 M) | ||
نوع مقاله: Case Report(s) | ||
شناسه دیجیتال (DOI): 10.30476/mejc.2020.78666.0 | ||
نویسندگان | ||
Mohammadreza Bordbar1؛ Nader Shakibazad* 1، 2؛ Hadi Mottaghipisheh3؛ Mahdi Shahriari3؛ Soheila Zareifar1؛ Omid Reza Zekavat1 | ||
1Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
2Department of Pediatric Hematology and Oncology, Bushehr University of Medical Sciences, Bushehr, Iran | ||
3Department of Pediatrics, Division of Pediatric Hematology and Oncology, Shiraz University of Medical Sciences, Shiraz, Iran | ||
چکیده | ||
Acute lymphoblastic leukemia has several presentations associated with bone marrow and extramedullary involvement. The unusual presentation may be due to the infiltration of leukemic cells in any organ. An 11-year-old girl presented with fever and vomiting, since one day before admission after starfish biting during swimming. Her vital signs were: blood pressure 150/100 mmHg, pulse 98 beats per minute, respiration 18 breathes per minute, and temperature 37.2 °C (99 F). Laboratory work-up showed blood urea nitrogen 38 mg/dl and creatinine 2.8 mg/dl. In peripheral blood smear, few atypical cells, mild anemia (Hb: 9.2 g/dl), and mild thrombocytopenia (Platelet: 109,000/μL) were detected. Bone marrow aspiration and immunophenotyping were in favor of acute precursor B cell type lymphoblastic leukemia. The patient had a favorable response to treatment after initiating high-risk chemotherapy. Therefore, acute renal failure can be a rare initial presentation of acute lymphoblastic leukemia, and azotemia will improve with an early chemotherapy treatment. | ||
کلیدواژهها | ||
Renal failure؛ Acute lymphocytic leukemia؛ Precursor B-cell lymphoblastic leukemia؛ Azotemia | ||
اصل مقاله | ||
How to cite this article: Bordbar M, Shakibazad N, Mottaghipisheh H, Shahriari M, Zareifar S, Zekavat OR. Acute renal failure: A rare initial presentation of acute lymphoblastic leukemia. Middle East J Cancer. 2020;11(4): 512-5. doi: 10.30476/mejc.2020. 78666.0. | ||
مراجع | ||
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