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Mohamadi, M, Rojhani-Shirazi, Z, Asadsangabi, R, Rahimi-Jaberi, A. (1399). Proton Magnetic Resonance Spectroscopy to Detect Correlations between Clinical Symptoms and Brain Metabolite Levels in Patients with Tension-type Headache. سامانه مدیریت نشریات علمی, 10(5), 583-588. doi: 10.31661/jbpe.v0i0.1039
M Mohamadi; Z Rojhani-Shirazi; R Asadsangabi; A Rahimi-Jaberi. "Proton Magnetic Resonance Spectroscopy to Detect Correlations between Clinical Symptoms and Brain Metabolite Levels in Patients with Tension-type Headache". سامانه مدیریت نشریات علمی, 10, 5, 1399, 583-588. doi: 10.31661/jbpe.v0i0.1039
Mohamadi, M, Rojhani-Shirazi, Z, Asadsangabi, R, Rahimi-Jaberi, A. (1399). 'Proton Magnetic Resonance Spectroscopy to Detect Correlations between Clinical Symptoms and Brain Metabolite Levels in Patients with Tension-type Headache', سامانه مدیریت نشریات علمی, 10(5), pp. 583-588. doi: 10.31661/jbpe.v0i0.1039
Mohamadi, M, Rojhani-Shirazi, Z, Asadsangabi, R, Rahimi-Jaberi, A. Proton Magnetic Resonance Spectroscopy to Detect Correlations between Clinical Symptoms and Brain Metabolite Levels in Patients with Tension-type Headache. سامانه مدیریت نشریات علمی, 1399; 10(5): 583-588. doi: 10.31661/jbpe.v0i0.1039

Proton Magnetic Resonance Spectroscopy to Detect Correlations between Clinical Symptoms and Brain Metabolite Levels in Patients with Tension-type Headache

Journal of Biomedical Physics and Engineering
مقاله 7، دوره 10، شماره 5، دی 2020، صفحه 583-588    اصل مقاله (483.56 K)
نوع مقاله: Original Research
شناسه دیجیتال (DOI): 10.31661/jbpe.v0i0.1039
نویسندگان
M Mohamadi1؛ Z Rojhani-Shirazi* 2؛ R Asadsangabi3؛ A Rahimi-Jaberi4
1PhD, Student Research Committee, Department of Physical Therapy, School of Rehabilitation Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
2PhD, Rehabilitation Research Center, Department of Physical Therapy, School of Rehabilitation Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
3PhD, Department of Radiology, Davis School of Medicine, University of California, USA
4PhD, Department of Neurology, School of Medicine,Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Proton magnetic resonance spectroscopy (1HMRS) is a noninvasive method to quantify pain. A 1HMRS spectrum is a group of peaks at different radiofrequencies, showing proton nuclei in various chemical environments. These MR spectra provide information about metabolite concentrations, and make MRS a useful procedure to monitor metabolic fluctuations due to disease, and to track the efficacy of treatment.
Objective: This study aims to identify correlations between clinical symptoms in patients with tension-type headache (TTH) and concentrations of brain metabolites.
Material and Methods: In this observational study, twenty-four patients (4 men and 20 women) with chronic TTH were included. To evaluate their clinical symptoms, the number of trigger points, headache frequency and headache intensity were recorded. The levels of anxiety and depression were recorded with the Beck Anxiety Inventory (BAI) and Beck Depression Inventory II (BDI- II). Concentrations of brain metabolites were determined in the anterior cingulate cortex, thalamus and primary somatosensory cortex of left hemisphere with 1HMRS.
Results: There was a negative correlation between trigger point count and choline/creatine (Cho/Cr) ratio in the primary somatosensory cortex [r= −0.509, n= 24, p = 0.01]. There were no correlations between other clinical symptoms of TTH and concentrations of brain metabolites.
Conclusion: Patients with more trigger points had a lower Cho/Cr ratio, which may indicate alterations in brain metabolic activity.
کلیدواژه‌ها
Brain Mapping؛ Neuroplasticity؛ Pain؛ Anxiety؛ Depression؛ Magnetic Resonance Spectroscopy
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مراجع
  1. Panigrahy A, Nelson Jr MD, Bluml S. Magnetic resonance spectroscopy in pediatric neuroradiology: clinical and research applications. Pediatr Radiol. 2010;40:3-30. doi: 10.1007/s00247-009-1450-z. PubMed PMID: 19937238.
  2. Chang L, Munsaka SM, Kraft-Terry S, Ernst T. Magnetic resonance spectroscopy to assess neuroinflammation and neuropathic pain. J Neuroimmune Pharmacol. 2013;8:576-93. doi: 10.1007/s11481-013-9460-x. PubMed PMID: 23666436. PubMed PMCID: PMC3698315.
  3. Van Der Graaf M. In vivo magnetic resonance spectroscopy: basic methodology and clinical applications. Eur Biophys J. 2010;39:527-40. doi: 10.1007/s00249-009-0517-y. PubMed PMID: 19680645. PubMed PMCID: PMC2841275.
  4. Jansen JF, Backes WH, Nicolay K, Kooi ME. 1H MR spectroscopy of the brain: absolute quantification of metabolites. Radiology. 2006;240:318-32. doi: 10.1148/radiol.2402050314. PubMed PMID: 16864664.
  5. Tracey I. Can neuroimaging studies identify pain endophenotypes in humans? Nat Rev Neurol. 2011;7:173-81. doi: 10.1038/nrneurol.2011.4. PubMed PMID: 21304481.
  6. Grachev ID, Fredrickson BE, Apkarian AV. Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study. Pain. 2000;89:7-18. doi: 10.1016/s0304-3959(00)00340-7. PubMed PMID: 11113288.
  7. Zhao X, Xu M, Jorgenson K, Kong J. Neurochemical changes in patients with chronic low back pain detected by proton magnetic resonance spectroscopy: A systematic review. Neuroimage Clin. 2017;13:33-8. doi: 10.1016/j.nicl.2016.11.006. PubMed PMID: 27920977. PubMed PMCID: PMC5126149.
  8. Grachev ID, Thomas PS, Ramachandran TS. Decreased levels of N-acetylaspartate in dorsolateral prefrontal cortex in a case of intractable severe sympathetically mediated chronic pain (complex regional pain syndrome, type I). Brain Cogn. 2002;49:102-13. doi: 10.1006/brcg.2001.1489.
  9. Pattany PM, Yezierski RP, Widerstrom-Noga EG, Bowen BC, Martinez-Arizala A, Garcia BR, et al. Proton magnetic resonance spectroscopy of the thalamus in patients with chronic neuropathic pain after spinal cord injury. AJNR Am J Neuroradiol. 2002;23:901-5. PubMed PMID: 12063213.
  10. Siddall PJ, Stanwell P, Woodhouse A, Somorjai RL, Dolenko B, Nikulin A, et al. Magnetic resonance spectroscopy detects biochemical changes in the brain associated with chronic low back pain: a preliminary report. Anesth Analg. 2006;102:1164-8. doi: 10.1213/01.ane.0000198333.22687.a6. PubMed PMID: 16551917.
  11. Lai TH, Protsenko E, Cheng YC, Loggia ML, Coppola G, Chen WT. Neural Plasticity in Common Forms of Chronic Headaches. Neural Plast. 2015;2015:205985. doi: 10.1155/2015/205985. PubMed PMID: 26366304. PubMed PMCID: PMC4558449.
  12. Jensen R, Stovner LJ. Epidemiology and comorbidity of headache. The Lancet Neurology. 2008;7:354-61.
  13. Dadfar M, Kalibatseva Z. Psychometric Properties of the Persian Version of the Short Beck Depression Inventory with Iranian Psychiatric Outpatients. Scientifica (Cairo). 2016;2016:8196463. doi: 10.1155/2016/8196463. PubMed PMID: 27293979. PubMed PMCID: PMC4886104.
  14. Khesht-Masjedi MF, Omar Z, Masoleh SMK. Psychometrics properties of the Persian version of Beck Anxiety Inventory in North of Iranian adolescents. International Journal of Educational and Psychological Researches. 2015;1:145. doi: 10.4103/2395-2296.152233.
  15. Gussew A, Rzanny R, Gullmar D, Scholle HC, Reichenbach JR. 1H-MR spectroscopic detection of metabolic changes in pain processing brain regions in the presence of non-specific chronic low back pain. Neuroimage. 2011;54:1315-23. doi: 10.1016/j.neuroimage.2010.09.039. PubMed PMID: 20869447.
  16. Petrou M, Harris RE, Foerster BR, McLean SA, Sen A, Clauw DJ, et al. Proton MR spectroscopy in the evaluation of cerebral metabolism in patients with fibromyalgia: comparison with healthy controls and correlation with symptom severity. AJNR Am J Neuroradiol. 2008;29:913-8. doi: 10.3174/ajnr.A0959. PubMed PMID: 18339723.
  17. Castillo M, Kwock L, Mukherji SK. Clinical applications of proton MR spectroscopy. AJNR Am J Neuroradiol. 1996;17:1-15. PubMed PMID: 8770242.
  18. Picciotto MR, Higley MJ, Mineur YS. Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. Neuron. 2012;76:116-29. doi: 10.1016/j.neuron.2012.08.036. PubMed PMID: 23040810. PubMed PMCID: PMC3466476.
  19. Auer DP, Putz B, Kraft E, Lipinski B, Schill J, Holsboer F. Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study. Biol Psychiatry. 2000;47:305-13. doi: 10.1016/s0006-3223(99)00159-6. PubMed PMID: 10686265.
  20. Moon C-M, Jeong G-W. Brain morphological alterations and cellular metabolic changes in patients with generalized anxiety disorder: a combined DARTEL-based VBM and 1 H-MRS study. Magn Reson Imaging. 2016;34:429-36. doi: 10.1016/j.mri.2015.12.017.
  21. Li Y, Jakary A, Gillung E, Eisendrath S, Nelson SJ, Mukherjee P, et al. Evaluating metabolites in patients with major depressive disorder who received mindfulness-based cognitive therapy and healthy controls using short echo MRSI at 7 Tesla. Magnetic Resonance Materials in Physics, Biology and Medicine. 2016;29:523-33. doi: 10.1007/s10334-016-0526-7.
  22. As-Sanie S, Kim J, Schmidt-Wilcke T, Sundgren PC, Clauw DJ, Napadow V, et al. Functional connectivity is associated with altered brain chemistry in women with endometriosis-associated chronic pelvic pain. The Journal of Pain. 2016;17:1-13. doi: 10.1016/j.jpain.2015.09.008.
  23. Godlewska BR, Masaki C, Sharpley AL, Cowen PJ, Emir UE. Brain glutamate in medication-free depressed patients: a proton MRS study at 7 Tesla. Psychol Med. 2018;48:1731-7.
  24. Moon CM, Kang HK, Jeong GW. Metabolic change in the right dorsolateral prefrontal cortex and its correlation with symptom severity in patients with generalized anxiety disorder: Proton magnetic resonance spectroscopy at 3 T esla. Psychiatry Clin Neurosci. 2015;69:422-30.
  25. Delvecchio G, Stanley JA, Altamura AC, Brambilla P. Metabolic alterations in generalised anxiety disorder: a review of proton magnetic resonance spectroscopic studies. Epidemiol Psychiatr Sci. 2017;26:587-95. doi: 10.1017/S2045796017000361. PubMed PMID: 28789715.
  26. Harper DE, Ichesco E, Schrepf A, Halvorson M, Puiu T, Clauw DJ, et al. Relationships between brain metabolite levels, functional connectivity, and negative mood in urologic chronic pelvic pain syndrome patients compared to controls: A MAPP research network study. Neuroimage Clin. 2018;17:570-8. doi: 10.1016/j.nicl.2017.11.014. PubMed PMID: 29201643. PubMed PMCID: PMC5702874.
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