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Zika Virus Infection and Colorectal Involvement | ||
| Iranian Journal of Colorectal Research | ||
| مقاله 8، دوره 7، شماره 2، شهریور 2019، صفحه 1-1 اصل مقاله (66.72 K) | ||
| نوع مقاله: Letter to the Editor | ||
| شناسه دیجیتال (DOI): 10.5812/acr.93108. | ||
| نویسنده | ||
| Viroj Wiwanitkit | ||
| Dr DY Patil University, Pune, India | ||
| چکیده | ||
| In medicine, the clinical spectrum of vector-borne dis- eases is an important issue. In particular, the colorectal in- volvement of these diseases has attracted much interest. In a previous publication, the interrelationship between the dengue virus and colorectal disease was explored (1). In the present article, the author would like to highlight the importance of investigating the relationship between Zika virus infection and colorectal disease. Zika virus disease is an emerging vector-borne disease presently considered as a significant public health prob- lem. As a new disease, further clinical research on this condition is still required. To the best of our knowledge, the colorectal presentation of Zika virus infection is yet to be reported. Nevertheless, it has already been ascertained that the Zika virus can infect the colorectal mucosa (2). In a recent report by Li et al. the Zika virus was reported to be able to infect rectal mucosa, with this pathology being re- lated to the fecal shedding of the virus (2). The Zika virus can also be detected using rectal swabs (3, 4); a recent re- port demonstrated that rectal swab samples led to positive viral tests in 10% of patients infected with the Zika virus (4). Rectal infection with the Zika virus can explain the dis- ease transmission via homosexual contact, which is an im- portant mode of Zika virus infection (5). It can also im- ply the necessity for infection control during any medical procedure involving the colorectal area. Finally, it is an in- teresting research issue to follow up whether any clinical problems are caused by Zika virus infection at the colorec- tal mucosa | ||
| کلیدواژه‌ها | ||
| Zika؛ Colorectum؛ Infction | ||
| مراجع | ||
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1. Wiwanitkit V. Dengue and Colorectal Disease. Ann Colorectal Res. 2019;7(1). e87992. doi: 10.5812/acr.87992.
2. Li C, Deng YQ, Zu S, Quanquin N, Shang J, Tian M, et al. Zika virus shedding in the stool and infection through the anorectal mucosa in mice. Emerg Microbes Infect. 2018;7(1):169. doi: 10.1038/s41426-018-0170- 6. [PubMed: 30333476]. [PubMed Central: PMC6193040].
3. Calvet GA, Kara EO, Giozza SP, Botto-Menezes CHA, Gaillard P, de Oliveira Franca RF, et al. Study on the persistence of Zika virus (ZIKV) in body fluids of patients with ZIKV infection in Brazil. BMC Infect Dis. 2018;18(1):49. doi: 10.1186/s12879-018-2965-4. [PubMed: 29357841]. [PubMed Central: PMC5778641].
4. Botto-Menezes CHA, Neto AM, Calvet GA, Kara EO, Lacerda MVG, Castilho MDC, et al. Zika Virus in Rectal Swab Samples. Emerg Infect Dis. 2019;25(5):951–4. doi: 10.3201/eid2505.180904. [PubMed: 31002058]. [PubMed Central: PMC6478207].
5. Sookaromdee P, Wiwanitkit V. Homosexual and Zika virus infection: Is it a new start of new problem for gay? Indian J Sex Transm Dis AIDS. 2018;39(1):61–2. doi: 10.4103/ijstd.IJSTD_65_16. [PubMed: 30187030]. [PubMed Central: PMC6111638]. | ||
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