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J Varas Lorenzo, Modesto, Munoz Agel, Fernando, Abad Belando, Ramon, Mengual, Elena. (1398). Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems. سامانه مدیریت نشریات علمی, 7(2), 1-7. doi: 10.5812/acr.88004.
Modesto J Varas Lorenzo; Fernando Munoz Agel; Ramon Abad Belando; Elena Sanchez-Vizcaino Mengual. "Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems". سامانه مدیریت نشریات علمی, 7, 2, 1398, 1-7. doi: 10.5812/acr.88004.
J Varas Lorenzo, Modesto, Munoz Agel, Fernando, Abad Belando, Ramon, Mengual, Elena. (1398). 'Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems', سامانه مدیریت نشریات علمی, 7(2), pp. 1-7. doi: 10.5812/acr.88004.
J Varas Lorenzo, Modesto, Munoz Agel, Fernando, Abad Belando, Ramon, Mengual, Elena. Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems. سامانه مدیریت نشریات علمی, 1398; 7(2): 1-7. doi: 10.5812/acr.88004.

Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems

Iranian Journal of Colorectal Research
مقاله 4، دوره 7، شماره 2، شهریور 2019، صفحه 1-7    اصل مقاله (115.87 K)
نوع مقاله: Research/Original Article
شناسه دیجیتال (DOI): 10.5812/acr.88004.
نویسندگان
Modesto J Varas Lorenzo1؛ Fernando Munoz Agel2؛ Ramon Abad Belando2؛ Elena Sanchez-Vizcaino Mengual3
1Echoendoscopy Unit and Department of Gastroenterology, Teknon Medical Center, Barcelona, Spain
2Echoendoscopy Unit and Department of Gastroenterology, Hospital Sanitas CIMA, Barcelona, Spain
3PMO, i2e3 Biomedical Research Institute, Barcelona, Spain
چکیده
Background: Carcinoid tumors are the most common neuroendocrine tumors. In recent years, these tumors have had an increase
in incidence, which is probably due to a higher number of them being incidentally found as a result of the rise of preventive
medicine.
Objectives: This study aimed to analyze a series of digestive carcinoid tumors detected by conventional endoscopy and/or echoendoscopy
to evaluate the prevalence of those located in the colon and rectum, and subsequently make a comparison with data available
in the literature.
Methods: In this retrospective, multicenter study (two centers), the clinical records of 100 white patients with more than 100 digestive
carcinoid tumors (some multiple) diagnosed from 1994 to 2018 were reviewed.
Results: The mean age of presentation was 52 years and 57% of the patients were men. The mean tumor size was 10 mm. The localization
of the tumors was: stomach 43% (n = 43); duodenum 5% (n = 5); intestine 8% (n = 8); appendix 14% (n = 14); colon 4% (n = 4);
rectum 19% (n = 19); pancreas 3% (n = 3); liver 2% (n = 2); gallbladder 1% (n = 1); primary tumor of unknown origin 1% (n = 1). Most
multifocal tumors were in the stomach (20%; n = 20), followed by the duodenum (1%; n = 1) and intestine (1%; n = 1). Metastases and
carcinoid syndrome were observed in 6% and 5% of the cases, respectively. General survival at the closure of the study was 80%.
Conclusions: Age and sex were similar to those described in the literature, while the colon and rectum represented 23% of all carcinoid
tumors. There was a predominance of gastroduodenal and rectal carcinoid tumors, probably because the series analyzed
was essentially endoscopic. In comparison with the literature, less cases of metastases or carcinoid syndrome were recorded and
survival was greater, perhaps due to earlier diagnosis and treatment.
کلیدواژه‌ها
Carcinoid Tumors؛ Neuroendocrine Tumor؛ Carcinoid Syndrome؛ Colon؛ Rectum؛ Gastrointestinal System؛ Hepatobiliary System
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