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Abbasi, Reza, Zomorodian, Kamiar, Zare Shahrabadi, Zahra, Saadat, Farshid, Nabavizadeh, Seyed Hesamedin, Esmaeilzadeh, Hossein, Alyasin, Sohila. (1398). IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis. سامانه مدیریت نشریات علمی, 16(4), 321-326. doi: 10.22034/iji.2019.80283
Reza Abbasi; Kamiar Zomorodian; Zahra Zare Shahrabadi; Farshid Saadat; Seyed Hesamedin Nabavizadeh; Hossein Esmaeilzadeh; Sohila Alyasin. "IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis". سامانه مدیریت نشریات علمی, 16, 4, 1398, 321-326. doi: 10.22034/iji.2019.80283
Abbasi, Reza, Zomorodian, Kamiar, Zare Shahrabadi, Zahra, Saadat, Farshid, Nabavizadeh, Seyed Hesamedin, Esmaeilzadeh, Hossein, Alyasin, Sohila. (1398). 'IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis', سامانه مدیریت نشریات علمی, 16(4), pp. 321-326. doi: 10.22034/iji.2019.80283
Abbasi, Reza, Zomorodian, Kamiar, Zare Shahrabadi, Zahra, Saadat, Farshid, Nabavizadeh, Seyed Hesamedin, Esmaeilzadeh, Hossein, Alyasin, Sohila. IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis. سامانه مدیریت نشریات علمی, 1398; 16(4): 321-326. doi: 10.22034/iji.2019.80283

IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis

Iranian Journal of Immunology
مقاله 6، دوره 16، شماره 4، اسفند 2019، صفحه 321-326    اصل مقاله (177.28 K)
نوع مقاله: Short Paper
شناسه دیجیتال (DOI): 10.22034/iji.2019.80283
نویسندگان
Reza Abbasi1، 2؛ Kamiar Zomorodian3؛ Zahra Zare Shahrabadi4؛ Farshid Saadat5؛ Seyed Hesamedin Nabavizadeh1؛ Hossein Esmaeilzadeh1؛ Sohila Alyasin* 1
1Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2Department of Pediatrics Allergy and Immunology, Yasuj University of Medical Sciences, Yasuj, Iran
3Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4Department of Parasitology and Mycology, School of Public Health, Shiraz University of Medical Sciences, Shiraz, Iran
5Department of Immunology, School of Public Health, Guilan University of Medical Sciences, Guilan, Iran
چکیده
Background: Fungal aeroallergens might sensitize the airway which in turn produces a specific cytokine profile. Objective: To evaluate the IL-25 and IL-33 profile in patients with fungal allergic rhinitis. Methods: The present study examined patients who were evaluated due to allergic rhinitis (AR) at Emam Reza Hospital of Shiraz, Iran. The allergic patients were categorized based on the skin prick test. Blood samples were collected and allergen-specific IgE and cytokine profiles were analyzed. Results: 184 patients were enrolled in the study and in 35 of whom fungal rhinitis was confirmed. The levels of specific IgE in patients with fungal allergy were statistically significant compared to those in the control group (p<0.000). However, there were no significant differences in IL-25 and IL-33 levels between fungal and none-fungal AR patients. Conclusion: Chronic fungal challenge might regulate innate system cytokines in severe persistent AR.
کلیدواژه‌ها
Allergic Fungal Sinusitis؛ Interleukin-25؛ Interleukin-33؛ IgE
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