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Influence of Parental Exposure to Risk Factors in the Occurrence of Oral Clefts | ||
| Journal of Dentistry | ||
| مقاله 7، دوره 21، شماره 2 - شماره پیاپی 67، شهریور 2020، صفحه 119-126 اصل مقاله (431.44 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/dentjods.2019.77620.0 | ||
| نویسندگان | ||
| Sandra Alto Eacute1؛ Alvaro Henrique Borges2؛ Ana Thereza de Saboia Campos Neves3؛ Andreza Maria Fábio Aranha4؛ Alexandre Meireles Borba5؛ Mariano Martinez Espinosa6؛ Luiz Evaristo Ricci Volpato* 4 | ||
| 1Dept. of Public Health, Nursery School, University of Cuiabá, Cuiabá, Brazil. | ||
| 2Dept. of Endodontics, Dental School, University of Cuiabá, Cuiabá, Brazil. | ||
| 3Dept. of Pediatric Dentistry, Dental School, University of Cuiabá, Cuiabá, Brazil. | ||
| 4Dept. of Pediatric Dentistry, Dental School, University of Cuiabá, Cuiabá, Brazil | ||
| 5Dept. of Surgery, Dental School, University of Cuiabá, Cuiabá, Brazil. | ||
| 6Dept. of Statistics, Federal University of Mato Grosso, Cuiabá, Brazil. | ||
| چکیده | ||
| Statement of the Problem: Non-syndromic cleft lip and palate are the most frequent craniofacial abnormalities in humans. The genetic, environmental and behavioral factors involved in this malformation must be clarified in different parts of the globe in the view of implementing preventive measures. Purpose: To analyze the influence of parental exposure to risk factors on the occurrence of oral clefts. Materials and Method: A case-control study was conducted with 150 mothers of oral cleft children paired by the children’s gender to 300 mothers of children without congenital anomalies from Mato Grosso, Brazil, for the study of the variables: gender and race/color of the children; parental educational level; age; number of pregnancies; prenatal care; obesity; stress; diabetes; hypertension; use of medications, alcohol and illicit drugs; smoking and exposure to ionizing radiation during the first trimester of pregnancy. The results were analyzed in relation to the chances possibility of each variable for the occurrence of oral cleft through the bivariate and multivariate analysis by applying the model of logistic regression. Results: Passive smoking, obesity, exposure to ionizing radiation and use of antibiotics were associated with the presence of clefts. The use of folic acid and analgesics were identified as preventive factors. The father's low educational level was found as a risk factor, while the black race/color was a preventive factor; nevertheless these variables were not associated in the multivariate analysis. Conclusion: The results reinforce the need to follow the pregnant women, especially in the first trimester of pregnancy, in order to control the identified risk factors. Clinical Relevance: Knowing the factors associated with the occurrence of oral clefts and those associated with its prevention, it is possible to apply specific health promotion measures during pregnancy, which can result in the reduction of oral clefts’ occurrence. | ||
| کلیدواژه‌ها | ||
| Case-Control Studies؛ Cleft Lip؛ Cleft Palate؛ Risk Factors | ||
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| مراجع | ||
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1. Carinci F, Scapoli l, Palmieri A, Zollino I, Pezzetti F. Human genetic factors in nonsyndromic cleft lip and palate: an update. Int J Pediatr Otorhinolaryngol. 2007; 71: 1509–1519. [PubMed] [Google Scholar]
2. Mossey PA, Little J. Epidemiology of oral clefts: An international perspective. In: Wyszynski DF, editor. Cleft lip and palate: From origins to treatment. 1th ed. New York : Oxford University Press; 2002. pp. 127–158. [Google Scholar]
3. Rodrigues K, Sena MF, Roncalli AG, Ferreira MA. Prevalence of orofacial clefts and social factors in Brazil. Braz Oral Res. 2009; 23: 38–42. [PubMed] [Google Scholar]
4. Wehby GL. Advancing and prioritizing research on oral clefts in Brazil. J Pediatr (Rio J) 2013; 89: 112–115. [PubMed] [Google Scholar]
5. Lebby KD, Tan F, Brown CP. Maternal factors and disparities associated with oral clefts. Ethn Dis. 2010; 20(1 Suppl 1): 146–149. [PMC free article] [PubMed] [Google Scholar]
6. Leite M, Albieri V, Kjaer SK, Jensen A. Maternal smoking in pregnancy and risk for congenital malformations: results of a Danish register-based cohort study. Acta Obstet Gynecol Scand. 2014; 93: 825–834. [PubMed] [Google Scholar]
7. Mostafa T. Cigarette smoking and male infertility. JAR. 2010; 1: 179–186. [Google Scholar]
8. Rocha RS, Bezerra SC, Lima JWO, Costa FS. Consumo de medicamentos, álcool e fumo na gestação e avaliação dos riscos teratogênicos. Rev Gaúcha Enfermagem. 2013; 34: 37–45. [PubMed] [Google Scholar]
9. Hutson JR, Stade B, Lehotay DC, Collier CP, Kapur BM. Folic acid transport to the human fetus is decreased in pregnancies with chronic alcohol exposure. PLoS One. 2012; 7: e38057. [PMC free article] [PubMed] [Google Scholar]
10. Martelli DR, Cruz KW, Barros LM, Silveira MF, Swerts MS, Martelli Júnior H. Maternal and paternal age, birth order and interpregnancy interval evaluation for cleft lip-palate. Braz J Otorhinolaryngol. 2010; 76: 107–112. [PubMed] [Google Scholar]
11. Figueiredo RF, Figueiredo N, Feguri A, Bieski I, Mello R, Espinosa M, Damazo AS. The role of the folic acid to the prevention of orofacial cleft: an epidemiological study. Oral Dis. 2015; 21: 240–247. [PubMed] [Google Scholar]
12. Acuña-González G, Medina-Solís CE, Maupomé G, Escoffie-Ramírez M, Hernández-Romano J, Márquez-Corona Mde L, et al. Family history and socioeconomic risk factors for non-syndromic cleft lip and palate: a matched case-control study in a less developed country. Biomedica. 2011; 31: 381–391. [PubMed] [Google Scholar]
13. Lidral AC, Moreno LM, Bullard SA. Genetic factors and orofacial clefting. Semin Orthod. 2008; 14: 103–114. [PMC free article] [PubMed] [Google Scholar]
14. Canfield MA, Honein MA, Yuskiv N, Xing J, Mai CT, Collins JS, et al. National estimates and race/ethnic-specific variation of selected birth defects in the united states, 1999-2001. Birth Defects Res a Clin Mol Teratol. 2006; 76: 747–756. [PubMed] [Google Scholar]
15. Cuozzo FD, Espinosa MM, da Silva KT, de Barros YB, Bandeca MC, Aranha AM, et al. Cleft lip and palate in a brazilian subpopulation. J Int Oral Health. 2013; 5: 15–20. [PMC free article] [PubMed] [Google Scholar]
16. Racusin D, Stevens B, Campbell G, Aagaard KM. Obesity and the risk and detection of fetal malformations. Semin Perinatol. 2012; 36: 213–221. [PMC free article] [PubMed] [Google Scholar]
17. Marengo L, Farag NH, Canfield M. Body mass index and birth defects: texas, 2005-2008. Matern Child Health J. 2013; 17: 1898–1907. [PubMed] [Google Scholar]
18. Block SR, Watkins SM, Salemi JL, Rutkowski R, Tanner JP, Correia JA, et al. Maternal pre-pregnancy body mass index and risk of selected birth defects: evidence of a dose-response relationship. Paediatr Perinat Epidemiol. 2013; 27: 521–531. [PubMed] [Google Scholar]
19. Mølgaard-Nielsen D, Hviid A. Maternal use of antibiotics and the risk of orofacial clefts: a nationwide cohort study. Pharmacoepidemiol Drug Saf. 2012; 21: 246–253. [PubMed] [Google Scholar]
20. Patel SJ, Reede DL, Katz DS, Subramaniam R, Amorosa JK. Imaging the pregnant patient for nonobstetric conditions: algorithms and radiation dose considerations. Radiographics. 2007; 27: 1705–1722. [PubMed] [Google Scholar]
21. Rakotoarison RA, Rakotoarivony AE, Rabesandratana N, Razafindrabe JB, Andriambololona R, Andriambololo-Nivo R, et al. Cleft lip and palate in madagascar 1998-2007. Br J Oral Maxillofac Surg. 2012; 50: 430–434. [PubMed] [Google Scholar]
22. Brasil RJ. Instituto Brasileiro de Geografia e Estatística. Atlas do censo demográfico 2010. 1th ed. Rio de Janeiro : IBGE; 2013. p. 109. [Google Scholar]
23. Vanz AP, Ribeiro NR. Listening to the mothers of individuals with oral fissures. Rev Esc Enferm USP. 2011; 45: 596–602. [PubMed] [Google Scholar]
24. Machado M, Pagliaro H, Baruzzi RG. Demographic profile of the Hupd'äh, a Maku people living in the Upper Rio Negro Region, State of Amazonas, Brazil (2000-2003) Rev Bras Estud Popul. 2009; 26: 37–50. [Google Scholar]
25. Pagliaro H. The demographic revolution among brazilian indigenous peoples: the case of the kayabí in the xingu indian reservation, mato grosso state, brazil, 1970-2007. Cad Saude Publica. 2010; 26: 579–590. [PubMed] [Google Scholar]
26. Genisca AE, Frías JL, Broussard CS, Honein MA, Lammer EJ, Moore CA, et al. Orofacial Clefts In The National Birth Defects Prevention Study, 1997-2004. Am J Med Genet A. 2009; 149: 1149–1158. [PMC free article] [PubMed] [Google Scholar]
27. Oliveira NP, Moi GP, Atanaka-Santos M, Silva AM, Pignati WA. Congenital defects in the cities with high use of pesticides in the state of Mato Grosso, Brazil. Cien Saude Colet. 2014; 19: 4123–4130. [PubMed] [Google Scholar]
28. Stott-Miller M, Heike CL, Kratz M, Starr JR. Increased risk of orofacial clefts associated with maternal obesity: case-control study and monte carlo-based bias analysis. Paediatr Perinat Epidemiol. 2010; 24: 502–512. [PMC free article] [PubMed] [Google Scholar]
29. van Beynum IM, Kapusta L, Bakker MK, den Heijer M, Blom HJ, de Walle HE. Protective effect of periconceptional folic acid supplements on the risk of congenital heart defects: a registry-based case-control study in the northern netherlands. Eur Heart J. 2010; 31: 464–471. [PubMed] [Google Scholar]
30. Wallace GH, Arellano JM, Gruner TM. Non-syndromic cleft lip and palate: could stress be a causal factor? Women Birth. 2011; 24: 40–46. [PubMed] [Google Scholar] | ||
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