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Ebrahimnejad Gorji, K, Abedi Firouzjah, R, Khanzadeh, F, Abdi-Goushbolagh, N, Banaei, A, Ataei, Gh. (1398). Estimating the Absorbed Dose of Organs in Pediatric Imaging of 99mTc-DTPA Radiopharmaceutical using MIRDOSE Software. سامانه مدیریت نشریات علمی, 9(3), 285-294. doi: 10.31661/jbpe.v0i0.984
K Ebrahimnejad Gorji; R Abedi Firouzjah; F Khanzadeh; N Abdi-Goushbolagh; A Banaei; Gh Ataei. "Estimating the Absorbed Dose of Organs in Pediatric Imaging of 99mTc-DTPA Radiopharmaceutical using MIRDOSE Software". سامانه مدیریت نشریات علمی, 9, 3, 1398, 285-294. doi: 10.31661/jbpe.v0i0.984
Ebrahimnejad Gorji, K, Abedi Firouzjah, R, Khanzadeh, F, Abdi-Goushbolagh, N, Banaei, A, Ataei, Gh. (1398). 'Estimating the Absorbed Dose of Organs in Pediatric Imaging of 99mTc-DTPA Radiopharmaceutical using MIRDOSE Software', سامانه مدیریت نشریات علمی, 9(3), pp. 285-294. doi: 10.31661/jbpe.v0i0.984
Ebrahimnejad Gorji, K, Abedi Firouzjah, R, Khanzadeh, F, Abdi-Goushbolagh, N, Banaei, A, Ataei, Gh. Estimating the Absorbed Dose of Organs in Pediatric Imaging of 99mTc-DTPA Radiopharmaceutical using MIRDOSE Software. سامانه مدیریت نشریات علمی, 1398; 9(3): 285-294. doi: 10.31661/jbpe.v0i0.984

Estimating the Absorbed Dose of Organs in Pediatric Imaging of 99mTc-DTPA Radiopharmaceutical using MIRDOSE Software

Journal of Biomedical Physics and Engineering
مقاله 5، دوره 9، شماره 3، مرداد و شهریور 2019، صفحه 285-294    اصل مقاله (627.2 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.31661/jbpe.v0i0.984
نویسندگان
K Ebrahimnejad Gorji1؛ R Abedi Firouzjah2؛ F Khanzadeh2؛ N Abdi-Goushbolagh3؛ A Banaei4؛ Gh Ataei* 5
1Department of Medical Physics Radiobiology and Radiation Protection, Babol University of Medical Sciences, Babol, Iran
2Department of Medical Radiation, Science and Research Branch, Islamic Azad University, Tehran, Iran
3Department of Medical Physics, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
5Department of Radiology Technology, Faculty of Paramedical Sciences, Babol University of Medical Science, Babol, Iran
چکیده
Introduction: In this study, organ radiation doses were calculated for the renal agent 99mTc-DTPA in children. Bio-kinetic energy of 99mTc-DTPA was evaluated by scintigraphy and estimates for absorbed radiation dose were provided using standard medical internal radiation dosimetry (MIRD) techniques.Material and Methods: In this applied research, fourteen children patients (6 males and 8 females) were imaged using a series of planar and SPECT images after injecting with technetium-99m diethylenetriaminepentaacetic acid (99mTc-DTPA). A hybrid planar/SPECT method was used to plot time-activity curves to obtain the residence time of the source organs and also MIRDOSE software was used to calculate the absorbed dose of every organ. P-values were calculated using t-tests in order to make a comparison between the adsorbed doses of male and female groups..Results: Mean absorbed doses (µGy/MBq) for urinary bladder wall, kidneys, gonads, liver and adrenals were 213.5±47.8, 12.97±6.23, 12.0±2.5, 4.29±1.47, and 3.31±0.96, respectively. Furthermore, the mean effective dose was 17.5±3.7 µSv/MBq. There was not any significant difference in the mean absorbed dose of the two groups.Conclusion: Bladder cumulated activity was the most contribution in the effective dose of patients scanned with 99mTc-DTPA. Using a hybrid planar/SPECT method can cause an increase in accumulated activity accuracy for the region of interest. Moreover, patient-specified internal dosimetry is recommended.
کلیدواژه‌ها
Internal Dosimetry؛ Hybrid Planar/SPECT Method؛ MIRDOSE Software؛ 99mTc-DTPA
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