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Reliability of Imprint Cytology and Frozen Sections for Demonstrating Free Surgical Margins in the Periocular Basal Cell Carcinoma | ||
| Middle East Journal of Cancer | ||
| مقاله 5، دوره 10، شماره 4 - شماره پیاپی 40، دی 2019، صفحه 314-318 اصل مقاله (1.65 M) | ||
| نوع مقاله: Original Article(s) | ||
| شناسه دیجیتال (DOI): 10.30476/mejc.2019.83407.1161 | ||
| نویسندگان | ||
| Bahram Eshraghi1؛ Mansooreh Jamshidian-Tehrani* 1؛ Seyed Mohsen Rafizadeh1؛ Hadi Ghadimi1؛ Maral Mokhtari2؛ Morteza Naderan1؛ Fahimeh Asadi Amoli3؛ Zohreh Nozarian3؛ Abolfazl Kasaee1 | ||
| 1Eye Research Center, Farabi Eye Hospital, Department of Ophthalmology, Tehran University of Medical Sciences, Tehran, Iran | ||
| 2Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 3Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran | ||
| چکیده | ||
| Purpose: The present was conducted to measure the sensitivity and specificity of imprint cytology (IC) and frozen section (FS) in the evaluation of margin involvement of periocular basal cell carcinoma (BCC). Methods: This cross-sectional study was conducted on 36 patients who underwent an excisional biopsy of periocular BCC. The surgical margins of each excised mass were tested for involvement by tumoral cells using three pathologic methods as follows. Samples were obtained for IC from the marginal territory of the tumor. Then, FS samples were obtained and the tissue was prepared for permanent histopathologic evaluation, the results of which were considered as the gold standard to compare two other methods. Sensitivity, specificity, positive predictive value, and negative predictive value of each method were calculated accordingly. Results: Thirty-six patients (20 males and 16 females) with the mean age of 73±12 years who had periocular BCC were enrolled and a total of 121 samples were obtained from the margins. The sensitivity and specificity of FS were 94.3 and 97.7% and of IC were 51.4 and 84.9%, respectively. Also, Positive and negative predictive value for FS were 94.3 and 97.7 and for IC were 58.1 and 81.1%, respectively. Conclusions: Although less expensive and more feasible than FS, IC lacks diagnostic accuracy for demarcating the extent of resection of eyelid BCC. | ||
| کلیدواژه‌ها | ||
| Basal cell carcinoma؛ Eyelid tumors؛ Frozen section؛ Imprint cytology | ||
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آمار تعداد مشاهده مقاله: 3,487 تعداد دریافت فایل اصل مقاله: 2,031 |
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