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Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, Iran | ||
Women’s Health Bulletin | ||
مقاله 3، دوره 1، شماره 2، مهر 2014، صفحه 1-6 اصل مقاله (193.36 K) | ||
نوع مقاله: Research Article | ||
شناسه دیجیتال (DOI): 10.17795/whb-20124 | ||
نویسندگان | ||
Zamzam Paknahad* 1، 2؛ Azam Ahmadi Vasmehjani2؛ Mohammad Reza Maracy3 | ||
1Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, IR Iran | ||
2Department of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, IR Iran | ||
3Department of Epidemiology and Biostatistics,Faculty of Health, Isfahan University of Medical Sciences, Isfahan, IR Iran | ||
چکیده | ||
Background: Epidemiological studies showed that vitamin D deficiency is associated with components of metabolic syndrome. Objectives: The aim of the present study was to determine the association between serum 25 hydroxyvitamin D concentration and components of metabolic syndrome in Iranian adult women. Patients and Methods: This study was comprised of 156 women aged ≥ 30 years with at least three of the five criteria of metabolic syndromes. Serum 25-hydroxyvitamin D (25 (OH)D) levels and components of the metabolic syndrome were determined. Metabolic syndrome was defined according to NCEP/ATP III criteria. The subjects were classified into three groups according to their serum concentration of 25 (OH)D. Results: Mean of serum concentration of 25-hydroxyvitamin D was 20.5 ± 10.8 ng/mL with %54.5, 23.1% and 22.4% of subjects were deficient, insufficient and sufficient in vitamin D, respectively. After adjustment for age, BMI, physical activity, and ANCOVA, fasting blood sugar concentration was shown to be inversely associated with serum 25 (OH)D (P = 0.004). On the other hand HDL-C showed significant correlation across different groups of vitamin D status (P = 0.014). Waist Circumference had favorable changes, without any statistically significant correlation. Also no significant association was observed between other components of metabolic syndrome and 25 (OH)D in different groups. Conclusions: The components of metabolic syndrome are influenced by serum 25 (OH)D concentrations. The finding of this investigation revealed that FBS and HDL-C concentrations related to serum 25 (OH)D. Therefore, further longitudinal studies and randomized clinical trials are necessary to determine the possible role of vitamin D in prevention of diabetes and cardiovascular disease. | ||
کلیدواژهها | ||
Blood Fasting Sugar؛ Women؛ Vitamin D؛ Metabolic Syndrome | ||
آمار تعداد مشاهده مقاله: 179 تعداد دریافت فایل اصل مقاله: 160 |