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Foroughinia, Farzaneh, Borhani-Haghighi, Afshin, Jamshidi, Elaheh, Javanmardi, Haniyeh. (1397). Intracranial hemorrhage after carotid artery stenting in two patients taking omega-3 fatty acids with dual antiplatelet therapy: two case reports. سامانه مدیریت نشریات علمی, 5(1), 1-6. doi: 10.30476/tips.2019.81725.1005
Farzaneh Foroughinia; Afshin Borhani-Haghighi; Elaheh Jamshidi; Haniyeh Javanmardi. "Intracranial hemorrhage after carotid artery stenting in two patients taking omega-3 fatty acids with dual antiplatelet therapy: two case reports". سامانه مدیریت نشریات علمی, 5, 1, 1397, 1-6. doi: 10.30476/tips.2019.81725.1005
Foroughinia, Farzaneh, Borhani-Haghighi, Afshin, Jamshidi, Elaheh, Javanmardi, Haniyeh. (1397). 'Intracranial hemorrhage after carotid artery stenting in two patients taking omega-3 fatty acids with dual antiplatelet therapy: two case reports', سامانه مدیریت نشریات علمی, 5(1), pp. 1-6. doi: 10.30476/tips.2019.81725.1005
Foroughinia, Farzaneh, Borhani-Haghighi, Afshin, Jamshidi, Elaheh, Javanmardi, Haniyeh. Intracranial hemorrhage after carotid artery stenting in two patients taking omega-3 fatty acids with dual antiplatelet therapy: two case reports. سامانه مدیریت نشریات علمی, 1397; 5(1): 1-6. doi: 10.30476/tips.2019.81725.1005

Intracranial hemorrhage after carotid artery stenting in two patients taking omega-3 fatty acids with dual antiplatelet therapy: two case reports

Trends in Pharmaceutical Sciences
مقاله 1، دوره 5، شماره 1، خرداد 2019، صفحه 1-6    اصل مقاله (435.56 K)
نوع مقاله: Case Report
شناسه دیجیتال (DOI): 10.30476/tips.2019.81725.1005
نویسندگان
Farzaneh Foroughinia* 1؛ Afshin Borhani-Haghighi2؛ Elaheh Jamshidi3؛ Haniyeh Javanmardi3
1Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Department of Clinical Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
2Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Department of Neurology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Patients undergoing Carotid Artery Stenting (CAS) may encounter serious complications including Intracranial hemorrhage (ICH). ICH after carotid re-vascularization has been usually attributed to cerebral hyperperfusion syndrome (CHS) and it is reported as a significant cause of mortality and morbidity. Factors mentioned as risk factors for ICH after carotid intervention are preoperative hypertension, renal failure, bilateral carotid disease or contralateral carotid occlusion, impaired cerebrovascular reserve, female gender, age, nonselective admission, increased Charlson comorbidities score. In this study, we report two cases of ICH after CAS in patients receiving dual antiplatelet regimen plus omega-3 fatty acids before and after carotid intervention. It seems that administration of omega 3 with other antiplatelets could augment inhibition of platelet aggregation and may increase the risk of ICH in patients undergoing CAS especially in those with several risk factors for ICH. These findings are important because of the wide availability of omega-3 supplements as an over-the-counter (OTC) drug and the propensity for usage of it in alternative medicine.
کلیدواژه‌ها
Intracranial Hemorrhage؛ Carotid artery stenting؛ Fatty Acids؛ Omega-3؛ Dual antiplatelets
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تعداد مشاهده مقاله: 10,418
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