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Noshadi, S, Atarod, M, Amouheidari, A, Felfeliyan, F, Shokrani, P. (1399). Evaluation of Therapeutic Properties of a Low Energy Electron Beam Plus Spoiler for Local Treatment of Mycosis Fungoides: A Monte Carlo Study. سامانه مدیریت نشریات علمی, 10(4), 441-448. doi: 10.31661/jbpe.v0i0.712
S Noshadi; M Atarod; A Amouheidari; F Felfeliyan; P Shokrani. "Evaluation of Therapeutic Properties of a Low Energy Electron Beam Plus Spoiler for Local Treatment of Mycosis Fungoides: A Monte Carlo Study". سامانه مدیریت نشریات علمی, 10, 4, 1399, 441-448. doi: 10.31661/jbpe.v0i0.712
Noshadi, S, Atarod, M, Amouheidari, A, Felfeliyan, F, Shokrani, P. (1399). 'Evaluation of Therapeutic Properties of a Low Energy Electron Beam Plus Spoiler for Local Treatment of Mycosis Fungoides: A Monte Carlo Study', سامانه مدیریت نشریات علمی, 10(4), pp. 441-448. doi: 10.31661/jbpe.v0i0.712
Noshadi, S, Atarod, M, Amouheidari, A, Felfeliyan, F, Shokrani, P. Evaluation of Therapeutic Properties of a Low Energy Electron Beam Plus Spoiler for Local Treatment of Mycosis Fungoides: A Monte Carlo Study. سامانه مدیریت نشریات علمی, 1399; 10(4): 441-448. doi: 10.31661/jbpe.v0i0.712

Evaluation of Therapeutic Properties of a Low Energy Electron Beam Plus Spoiler for Local Treatment of Mycosis Fungoides: A Monte Carlo Study

Journal of Biomedical Physics and Engineering
مقاله 6، دوره 10، شماره 4، آبان 2020، صفحه 441-448    اصل مقاله (1.65 M)
نوع مقاله: Original Research
شناسه دیجیتال (DOI): 10.31661/jbpe.v0i0.712
نویسندگان
S Noshadi1؛ M Atarod2؛ A Amouheidari3؛ F Felfeliyan1؛ P Shokrani* 4
1MSc, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2PhD, Department of Medical Physics and Radiology, Shahrekord University of Medical Sciences, Shahrekord, Iran
3MD, Department of Radiation Oncology, Milad Hospital, Isfahan, Iran
4PhD, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده
Background: When using low-energy electron beams for the treatment of skin lesions, such as Mycosis Fungoides (MF), a beam spoiler is used to decrease electron therapeutic depth (R90) while increasing the surface dose.
Objective: The aim of this study was to evaluate the characteristics of a 5 MeV electron beam when using a spoiler for the local treatment of MF skin lesions by Monte Carlo (MC) simulation.
Material and Methods: In this experimental study, a Siemens Primus treatment head and an acrylic spoiler, positioned at the end of applicator, were simulated using BEAMnrc, an EGSnrc user code. The modelled beam was validated by measurement using MP3-M water tank, Roos parallel plate chamber and Semi flex Chamber-31013 (all from PTW, Freiburg, Germany). For different spoiler thicknesses, dose distributions in water were calculated for 2 field sizes and were compared to those for the corresponding open fields.
Results: For a 1.3 cm spoiler, therapeutic range changed from 1.5 cm (open field) to 0.5 cm and 0.4 cm for 10 × 10 cm2 and 20 × 20 cm2 field sizes, respectively. Maximum increase in penumbra width was 2.8 and 3.8 cm for 10 × 10 cm2 and 20 × 20 cm2 field sizes, respectively. Maximum increase in bremsstrahlung contamination was %2 in both field sizes.
Conclusion: R90 decreased exponentially with increase in spoiler thickness. The effect of field size on penumbra was much larger for spoiled beam compared to the open beam. The results of this research can be applied to optimize the radiation treatment of MF patients in our hospital.
کلیدواژه‌ها
Penumbra؛ Spoiler؛ Electrons؛ Monte Carlo Method؛ Radiotherapy
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