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Epidemiology of Inflammatory Bowel Diseases in Iran and Asia; A Mini Review | ||
Iranian Journal of Medical Sciences | ||
مقاله 1، دوره 38، June Supplement 2013، فروردین 2013، صفحه 140-149 اصل مقاله (339.56 K) | ||
نوع مقاله: Review Article | ||
شناسه دیجیتال (DOI): 10.30476/ijms.2013.44096 | ||
نویسندگان | ||
Davood Mehrabani* 1؛ Ali Reza Safarpour2؛ Seyed Vahid Hosseini3 | ||
1Stem Cell and Transgenic Technology Research Center, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran | ||
2Colorectal Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran | ||
3Laparoscopy Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran | ||
چکیده | ||
The prevalence of inflammatory bowel diseases (IBDs) is set to stabilize in Western Europe and North America, as opposed to its increasing trend in developing countries in Asia. The epidemiology of IBDs in areas where the incidence and prevalence are relatively low provides an opportunity for researchers to determine the unknown aspects of them. In this review article, the PubMed and MEDLINE databases were searched from 1970 to 2012 and the epidemiological aspects assessed in Iranian articles were compared with identical subjects in other Asian countries. During this period, there were 21 documented articles on IBD epidemiology in Iran and 52 in Asia. According to the present review, CTLA-gene polymorphism and male/female ratio in ulcerative colitis (UC), incidence of extra-intestinal manifestations, extent of intestinal involvement, and family history in both UC and Crohn's disease (CD) seemed to be different between Asia and Iran. In contrast, the incidence of primary sclerosing cholangitis in IBD patients and association between NO2/CARD15 mutation and CD as C3435-T allele and UC were nearly the same. The rate of IBD has increased significantly in Iran, as has that of other Asian countries during the last decade. A thorough, well-designed, population-based, multi-regional epidemiologic study seems mandatory due to the substantial demographic and characteristic variability in IBD patients in our region. | ||
کلیدواژهها | ||
Inflammatory bowel disease؛ Epidemiology؛ Prevalence؛ Iran | ||
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