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The Effect of Citalopram and Colonazpam on Burning Mouth Syndrome | ||
Journal of Dentistry | ||
مقاله 6، دوره 9، Supplement 2008، دی 2008، صفحه 31-34 اصل مقاله (34.96 K) | ||
نوع مقاله: Original Article | ||
شناسه دیجیتال (DOI): 10.30476/dentjods.2019.43615 | ||
نویسندگان | ||
H. Ebrahimi* 1؛ S. Pourshahidi1؛ A. Andisheh Tadbir2 | ||
1Dept. of Oral Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. | ||
2Dept. of Oral Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. | ||
چکیده | ||
Statement of problem: Psychosocial factors are thought to play a role in burning mouth syndrome (BMS) and several therapeutic approaches for BMS are based on this consideration.Purpose: This paper evaluated the efficacy of the combined systemic administration of citalopram and clonazepam, as anti-depressant and anti-anxiety drugs, in the management of burning mouth syndrome and reduction of the burning sensation.Materials and Method: In this cross-sectional study, 80 subjects suffering from idiopathic burning mouth syndrome were enrolled. The patients underwent a thorough clinical examination. Oral symptoms before and after treatment were assessed using a Visual Analogue Scale. The mean duration of burning in our patients was 7 months. Systemic combination of citalopram (20 mg/daily) and clonazpam (0.25 mg/daily) was prescribed for all of them for 8 weeks. Then, the data were analysed, using Student’s t-test.Results: Of the 62 patients who completed the protocol, 38 reported complete remission of the oral burning sensation. However, 20 patients reported a little improvement, and four of them reported no improvement.Conclusion: These data suggest that citaloperam with colonazpam is effective in patients with BMS | ||
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