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Farahani, Mohammad, Safavi, Seyed Mohammadreza, Dianat, Omid, Khoramian Tusi, Somayeh, Younessian, Farnaz. (1394). Acid and Alkaline Phosphatase Levels in GCF during Orthodontic Tooth Movement. سامانه مدیریت نشریات علمی, 16(Supplement 3- September 2015), 237-245.
Mohammad Farahani; Seyed Mohammadreza Safavi; Omid Dianat; Somayeh Khoramian Tusi; Farnaz Younessian. "Acid and Alkaline Phosphatase Levels in GCF during Orthodontic Tooth Movement". سامانه مدیریت نشریات علمی, 16, Supplement 3- September 2015, 1394, 237-245.
Farahani, Mohammad, Safavi, Seyed Mohammadreza, Dianat, Omid, Khoramian Tusi, Somayeh, Younessian, Farnaz. (1394). 'Acid and Alkaline Phosphatase Levels in GCF during Orthodontic Tooth Movement', سامانه مدیریت نشریات علمی, 16(Supplement 3- September 2015), pp. 237-245.
Farahani, Mohammad, Safavi, Seyed Mohammadreza, Dianat, Omid, Khoramian Tusi, Somayeh, Younessian, Farnaz. Acid and Alkaline Phosphatase Levels in GCF during Orthodontic Tooth Movement. سامانه مدیریت نشریات علمی, 1394; 16(Supplement 3- September 2015): 237-245.

Acid and Alkaline Phosphatase Levels in GCF during Orthodontic Tooth Movement

Journal of Dentistry
مقاله 3، دوره 16، Supplement 3- September 2015، آذر 2015، صفحه 237-245    اصل مقاله (609.59 K)
نوع مقاله: Original Article
نویسندگان
Mohammad Farahani1؛ Seyed Mohammadreza Safavi2؛ Omid Dianat3؛ Somayeh Khoramian Tusi4؛ Farnaz Younessian* 5
1Dept. of Orthodontic, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2Dental Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3Dept. of Endodontic, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4Dept. of Pediatric, Dental School, Alborz University of Medical Sciences, Karaj, Iran.
5Dentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده
Statement of the Problem: The present constituents of gingival crevicular fluid (GCF) can reflect the changes occurring in underlying tissues. Considering variety of biologic bone markers, alkaline phosphatase and acid phosphatase have been examined as bone turn over markers in orthodontic tooth movement.Purpose: The current study designed in a longitudinal pattern to determine the changes of acid and alkaline phosphatase (ACP & ALP) in GCF during orthodontic tooth movement.Materials and Method: An upper canines from twelve patients (mean age: 14±2 years) undergoing extraction orthodontic treatment for distal movement served as the test tooth (DC), and its contralateral (CC) and antagonist (AC) canines were used as controls. The CC was included in orthodontic appliance without orthodontic force; the AC was free from any orthodontic appliance. The GCF around the experimental teeth was harvested from mesial and distal tooth sites immediately before appliance placement (T0), and 14 (T2) and 28 days (T3) after it and ALP and ACP concentration were determined spectrophotometrically.Results: ALP concentration was elevated significantly in DC and CC groups at days 14 and 28 compared with the AC. In DC group, the ALP was significantly greater in mesial sites than distal site, while no significant changes were found between both sites of CC. The peak level of ALP was observed in mesial sites of DC at T2. Regarding ACP, significant elevation of this enzyme was seen in DC group both in mesial and distal sites at T2 and T3. The peak level of this enzyme was seen at T2.Conclusion: Monitoring simultaneous changes of ALP and ACP levels in GCF can reflect the tissue responses occur in periodontium during bone formation and bone resorption during orthodontic tooth movement, respectively.
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