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Ghasemi, P, Sahraee, T, Mohammadi, A. (1397). Closed- and Open-loop Deep Brain Stimulation: Methods, Challenges, Current and Future Aspects. سامانه مدیریت نشریات علمی, 8(2), 209-216. doi: 10.31661/jbpe.v8i2.898
P Ghasemi; T Sahraee; A Mohammadi. "Closed- and Open-loop Deep Brain Stimulation: Methods, Challenges, Current and Future Aspects". سامانه مدیریت نشریات علمی, 8, 2, 1397, 209-216. doi: 10.31661/jbpe.v8i2.898
Ghasemi, P, Sahraee, T, Mohammadi, A. (1397). 'Closed- and Open-loop Deep Brain Stimulation: Methods, Challenges, Current and Future Aspects', سامانه مدیریت نشریات علمی, 8(2), pp. 209-216. doi: 10.31661/jbpe.v8i2.898
Ghasemi, P, Sahraee, T, Mohammadi, A. Closed- and Open-loop Deep Brain Stimulation: Methods, Challenges, Current and Future Aspects. سامانه مدیریت نشریات علمی, 1397; 8(2): 209-216. doi: 10.31661/jbpe.v8i2.898

Closed- and Open-loop Deep Brain Stimulation: Methods, Challenges, Current and Future Aspects

Journal of Biomedical Physics and Engineering
مقاله 8، دوره 8، شماره 2، شهریور 2018، صفحه 209-216    اصل مقاله (613.7 K)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.31661/jbpe.v8i2.898
نویسندگان
P Ghasemi1؛ T Sahraee2؛ A Mohammadi* 3
1Department of Electrical and Computer Engineering, Shahid Beheshti University, Tehran, Iran
2Department of Electronic Engineering, Tabriz University, Tabriz, Iran
3Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
چکیده
Deep brain stimulation (DBS) is known as the most effective technique in the treatment of neurodegenerative diseases, especially Parkinson disease (PD) and epilepsy. Relative healing and effective control of disease symptoms are the most significant reasons for the tangible tendency in use and development of this technology. Nevertheless, more cellular and molecular investigations are required to reveal the detailed mechanism of DBS. Here, we reviewed the methods, challenges and the ways to overcome the limitations of DBS. Also, challenges in probe fabrication technology, material selection, related mechanical stability and biocompatibility concerns are discussed. Finally, closed- and open-loop stimulation systems were compared.
کلیدواژه‌ها
DBS؛ Open-loop؛ Closed-loop؛ Probe؛ Parkinson's disease؛ Neural interface
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