LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,149
تعداد مقالات10,518
تعداد مشاهده مقاله45,416,262
تعداد دریافت فایل اصل مقاله11,292,116
Robatjazi, M, Tanha, K, Mahdavi, S R, Baghani, H R, Mirzaei, H R, Mousavi, M, Nafissi, N, Akbari, E. (1396). Monte Carlo Simulation of Electron Beams produced by LIAC Intraoperative Radiation Therapy Accelerator. سامانه مدیریت نشریات علمی, 8(1), 43-52.
M Robatjazi; K Tanha; S R Mahdavi; H R Baghani; H R Mirzaei; M Mousavi; N Nafissi; E Akbari. "Monte Carlo Simulation of Electron Beams produced by LIAC Intraoperative Radiation Therapy Accelerator". سامانه مدیریت نشریات علمی, 8, 1, 1396, 43-52.
Robatjazi, M, Tanha, K, Mahdavi, S R, Baghani, H R, Mirzaei, H R, Mousavi, M, Nafissi, N, Akbari, E. (1396). 'Monte Carlo Simulation of Electron Beams produced by LIAC Intraoperative Radiation Therapy Accelerator', سامانه مدیریت نشریات علمی, 8(1), pp. 43-52.
Robatjazi, M, Tanha, K, Mahdavi, S R, Baghani, H R, Mirzaei, H R, Mousavi, M, Nafissi, N, Akbari, E. Monte Carlo Simulation of Electron Beams produced by LIAC Intraoperative Radiation Therapy Accelerator. سامانه مدیریت نشریات علمی, 1396; 8(1): 43-52.

Monte Carlo Simulation of Electron Beams produced by LIAC Intraoperative Radiation Therapy Accelerator

Journal of Biomedical Physics and Engineering
مقاله 5، دوره 8، شماره 1، خرداد 2018، صفحه 43-52    اصل مقاله (1.94 M)
نوع مقاله: Original Research
نویسندگان
M Robatjazi1؛ K Tanha2؛ S R Mahdavi* 3؛ H R Baghani4؛ H R Mirzaei5؛ M Mousavi1؛ N Nafissi6؛ E Akbari7
1Medical Physics and Radiological Sciences Department, Sabzevar University of Medical Sciences, Sabzevar, Iran
2Persian Gulf Nuclear Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran
3Medical Physics Department, Iran University of Medical Sciences, Tehran, Iran
4Physics Department, School of Sciences, Hakim Sabzevari University, Sabzevar, Iran
5Radiation Therapy Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6Surgery Department, Iran University of Medical Sciences, Tehran, Iran
7Oncological Surgery Department, Shahid Beheshti University of Medical Sciences, Tehran, Iranv
چکیده
Background: One of the main problems of dedicated IORT accelerators is to determine dosimetric characteristics of the electron beams. Monte Carlo simulation of IORT accelerator head and produced beam will be useful to improve the accuracy of beam dosimetry.Materials and Methods: Liac accelerator head was modeled using the BEAMnrcMonte Carlo simulation system. Phase-space files were generated at the bottom of the applicators. These phase-space files were used as an input source in DOSXYZnrc and BEAMDP codes for dose calculation and analysis of the characteristic of the electron beams in all applicators and energies.Results: The results of Monte Carlo calculations are in very close agreement with the measurements. There is a decrease in the peak of the initial spectrum when electrons come from the end of accelerator wave guide to the end of applicator. By decreasing the applicator diameter, the mean energy of electron beam decreased. Using applicators and increasing their size, X-ray contamination will increase. The percentage of X-ray contamination increases by applicator diameter. This is related to the increase of the mean energy of electron beams.Conclusion: Application of PMMA collimator leads to, although well below accepted level, the production of bremsstrahlung. The results of this study showed that special design of LIAC head accompanying by PMMA collimator system cause to produce an electron beam with an individual dosimetric characteristic making it a useful tool for intraoperative radiotherapy purposes.
کلیدواژه‌ها
Monte Carlo Simulation؛ IORT؛ Photon Contamination؛ Dosimetry؛ LIAC
مراجع
  1. Baghani HR, Aghamiri SM, Mahdavi SR, Akbari ME, Mirzaei HR. Comparing the dosimetric characteristics of the electron beam from dedicated intraoperative and conventional radiotherapy accelerators. J Appl Clin Med Phys. 2015;16:5017. doi: 10.1120/jacmp.v16i2.5017. PubMed PMID: 26103175.
  2. Laitano RF, Guerra AS, Pimpinella M, Caporali C, Petrucci A. Charge collection efficiency in ionization chambers exposed to electron beams with high dose per pulse. Phys Med Biol. 2006;51:6419-36. doi.org/10.1088/0031-9155/51/24/009. PubMed PMID: 17148826.
  3. Di Martino F, Giannelli M, Traino AC, Lazzeri M. Ion recombination correction for very high dose-per-pulse high-energy electron beams. Med Phys. 2005;32:2204-10. doi.org/10.1118/1.1940167. PubMed PMID: 16121574.
  4. Righi S, Karaj E, Felici G, Di Martino F. Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation. J Appl Clin Med Phys. 2013;14:3678. PubMed PMID: 23318376.
  5. Iaccarino G, Strigari L, D’Andrea M, Bellesi L, Felici G, Ciccotelli A, et al. Monte Carlo simulation of electron beams generated by a 12 MeV dedicated mobile IORT accelerator. Phys Med Biol. 2011;56:4579-96. doi.org/10.1088/0031-9155/56/14/022. PubMed PMID: 21725139.
  6. Rogers DW, Faddegon BA, Ding GX, Ma CM, We J, Mackie TR. BEAM: a Monte Carlo code to simulate radiotherapy treatment units. Med Phys. 1995;22:503-24. doi.org/10.1118/1.597552. PubMed PMID: 7643786.
  7. Rogers D, Ma C, Walters B, Ding G, Sheikh-Bagheri D, Zhang G. BEAMnrc Users Manual National Research Council of Canada. NRCC Report PIRS-0509 (A) revK. 2002.
  8. Bielajew AF, Rogers D. PRESTA: the parameter reduced electron-step transport algorithm for electron Monte Carlo transport. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 1986;18:165-81. doi.org/10.1016/S0168-583X(86)80027-1.
  9. Walters B, Kawrakow I, Rogers D. DOSXYZnrc users manual. NRC Report PIRS. 2005;794.
  10. Low DA, Harms WB, Mutic S, Purdy JA. A technique for the quantitative evaluation of dose distributions. Med Phys. 1998;25:656-61. doi.org/10.1118/1.598248. PubMed PMID: 9608475.
  11. Low DA, Dempsey JF. Evaluation of the gamma dose distribution comparison method. Med Phys. 2003;30:2455-64. doi.org/10.1118/1.1598711. PubMed PMID: 14528967.
  12. Ma C, Rogers D. BEAMDP users manual. NRC Report PIRS-0509 (D). 1995.
  13. Bjork P, Nilsson P, Knoos T. Dosimetry characteristics of degraded electron beams investigated by Monte Carlo calculations in a setup for intraoperative radiation therapy. Phys Med Biol. 2002;47:239-56. doi.org/10.1088/0031-9155/47/2/305. PubMed PMID: 11837615.
  14. Mihailescu D, Pimpinella M, Guerra A, Laitano R. Comparison of measured and Monte Carlo calculated dose distributions for the NOVAC7® linear accelerator. Romanian Journal of Physics. 2006;51:729.
  15. Bjork P, Knoos T, Nilsson P. Influence of initial electron beam characteristics on monte carlo calculated absorbed dose distributions for linear accelerator electron beams. Phys Med Biol. 2002;47:4019-41. doi.org/10.1088/0031-9155/47/22/308. PubMed PMID: 12476980.
  16. Bjork P, Knoos T, Nilsson P, Larsson K. Design and dosimetry characteristics of a soft-docking system for intraoperative radiation therapy. Int J Radiat Oncol Biol Phys. 2000;47:527-33. doi.org/10.1016/S0360-3016(00)00456-9. PubMed PMID: 10802382.
  17. Pimpinella M, Mihailescu D, Guerra AS, Laitano RF. Dosimetric characteristics of electron beams produced by a mobile accelerator for IORT. Phys Med Biol. 2007;52:6197-214. doi.org/10.1088/0031-9155/52/20/008. PubMed PMID: 17921580.
  18. Beddar AS, Biggs PJ, Chang S, Ezzell GA, Faddegon BA, Hensley FW, et al. Intraoperative radiation therapy using mobile electron linear accelerators: Report of AAPM Radiation Therapy Committee Task Group No. 72. Medical physics. 2006;33:1476-89. doi.org/10.1118/1.2194447.
  19. Robatjazi M, Mahdavi SR, Takavr A, Baghani HR. Application of Gafchromic EBT2 film for intraoperative radiation therapy quality assurance. Phys Med. 2015;31:314-9. doi.org/10.1016/j.ejmp.2015.01.020. PubMed PMID: 25703011.
آمار
تعداد مشاهده مقاله: 1,127
تعداد دریافت فایل اصل مقاله: 266


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب