Soleimani, A, Rasta, S H, Banaei, T, Asgharsharghi Bonab, A. (1396). Effects of Laser Physical Parameters on Lesion Size in Retinal Photocoagulation Surgery: Clinical OCT and Experimental Study. سامانه مدیریت نشریات علمی, 7(4), 355-364.
A Soleimani; S H Rasta; T Banaei; A Asgharsharghi Bonab. "Effects of Laser Physical Parameters on Lesion Size in Retinal Photocoagulation Surgery: Clinical OCT and Experimental Study". سامانه مدیریت نشریات علمی, 7, 4, 1396, 355-364.
Soleimani, A, Rasta, S H, Banaei, T, Asgharsharghi Bonab, A. (1396). 'Effects of Laser Physical Parameters on Lesion Size in Retinal Photocoagulation Surgery: Clinical OCT and Experimental Study', سامانه مدیریت نشریات علمی, 7(4), pp. 355-364.
Soleimani, A, Rasta, S H, Banaei, T, Asgharsharghi Bonab, A. Effects of Laser Physical Parameters on Lesion Size in Retinal Photocoagulation Surgery: Clinical OCT and Experimental Study. سامانه مدیریت نشریات علمی, 1396; 7(4): 355-364.
Effects of Laser Physical Parameters on Lesion Size in Retinal Photocoagulation Surgery: Clinical OCT and Experimental Study
1Department of Medical Physics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2Medical Physics Department, Reza Radiotherapy Oncology Centre, Mashhad, Iran
3Stem Cell Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran
4Department of Medical Bioengineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
5School of Biomedical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK
6Retina Research Center, Mashhad University of Medical Science, Mashhad, Iran
7Research Unit, Sensory Biology & Organogenesis (SBO), Helmholtz Zentrum München, 85764 Neuherberg – Munich, Germany
چکیده
Introduction: The aim of the present study was to determine burn intensity in retinal laser photocoagulation based on laser parameters; wavelength, power, beam size and pulse duration, using Optical Coherence Tomography (OCT), fundus camera, physical eye model and computer simulation in a clinical study.Materials and Methods: Participants were 10 adult patients between 50-80 years with proliferative diabetic retinopathy. A multicolor-photo coagulator with 532 nm green and 672 nm red for retina photocoagulation in diabetic retinopathy was used to investigate the participants. Lesion size was measured for spot sizes 50 and 100 μm, with 100 and 150 mW laser power, and pulse duration 50 and 100 ms by OCT. Artificial eye and Zemax-optical design software were used with the same laser parameters.Results: Appearance of OCT and fundus images showed direct relationship between retina burn size and lesion intensity with exposure time and power and also reverse relationship with laser spot size. Compared to red wavelength, burn size and lesion intensity increased in green wavelength. On the other hand, results from physical eye model were the same as clinical examination shown. Laser spot size in retina with Zemax simulation demonstrated that red wavelength was greater than green one.Conclusion: This study showed shorter pulses provide decrease in duration of laser surgery with significantly reduced pain. Results and calculations described in this article can help clinicians adjusting the required total coagulated area, the number of lesions and pattern density.
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