LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,113
تعداد مقالات10,208
تعداد مشاهده مقاله40,779,986
تعداد دریافت فایل اصل مقاله8,803,891
Bahreyni-Toosi, M H, Zare, M H, Ale davood, A, Shakeri, M T, Soudmand, S. (1396). In-vitro Study of Photothermal Anticancer Activity of Carboxylated Multiwalled Carbon Nanotubes. سامانه مدیریت نشریات علمی, 7(4), 317-332.
M H Bahreyni-Toosi; M H Zare; A Ale davood; M T Shakeri; S Soudmand. "In-vitro Study of Photothermal Anticancer Activity of Carboxylated Multiwalled Carbon Nanotubes". سامانه مدیریت نشریات علمی, 7, 4, 1396, 317-332.
Bahreyni-Toosi, M H, Zare, M H, Ale davood, A, Shakeri, M T, Soudmand, S. (1396). 'In-vitro Study of Photothermal Anticancer Activity of Carboxylated Multiwalled Carbon Nanotubes', سامانه مدیریت نشریات علمی, 7(4), pp. 317-332.
Bahreyni-Toosi, M H, Zare, M H, Ale davood, A, Shakeri, M T, Soudmand, S. In-vitro Study of Photothermal Anticancer Activity of Carboxylated Multiwalled Carbon Nanotubes. سامانه مدیریت نشریات علمی, 1396; 7(4): 317-332.

In-vitro Study of Photothermal Anticancer Activity of Carboxylated Multiwalled Carbon Nanotubes

Journal of Biomedical Physics and Engineering
مقاله 2، دوره 7، شماره 4، اسفند 2017، صفحه 317-332    اصل مقاله (692 K)
نوع مقاله: Original Research
نویسندگان
M H Bahreyni-Toosi1؛ M H Zare* 2؛ A Ale davood3؛ M T Shakeri4؛ S Soudmand5
1Medical Physics Research Center, Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2Medical Physics Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3Cancer Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
5Medical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
چکیده
Background and Objective: Multi-walled Carbon Nano Tubes (MWCNTs) as an important element of nanosciences have a remarkable absorption in the region of NIR window (650-900 nm) which can overcome the limitations of deep treatment in photothermal therapy. To disperse MWCNTs in water, it is proposed to attach carboxylated functional group (-COOH) to MWCNTs in order to increase dispersivity in water.Materials and Methods: A stable suspension of MWCNTs-COOH with different concentrations (from 2.5 to 500 μg/ml) was prepared. Then, they were compared for their ability to increase temperature in the presence of 810 nm laser irradiation and through a wide range of radiation time (from 20 to 600 s) and three laser powers (1.5, 2 and 2.5 w). The temperature rise was recorded real time every 20 seconds by a precise thermometer.Results: Absorption spectrum of MWCNTs-COOH suspension was remarkably higher than water in a wavelength range of 200 to 1100 nm. For example, using the concentrations of 2.5 and 80 μg/ml of MWCNTs-COOH suspension caused a temperature elevation 2.35 and 9.23 times compared to water, respectively, upon 10 min laser irradiation and 2.5 w. Moreover, this predominance can be observed for 1.5 and 2 w radiation powers, too. Our findings show that the maximum of temperature increase was obtained at 80 μg/ml concentration of MWCNT-COOH suspension for three powers and through all periods of exposure time. Our results show that the minimum required parameters for a 5°C temperature increase (a 5°C temperature increase causes cell death) were achieved through 2.5 w, 28 μg/ml concentration and 20 second irradiation time in which both concentration and radiation times were relatively low.Conclusion: Our results showed that MWCNTs-COOH can be considered as a potent photothermal agent in targeted therapies. New strategies must be developed to minimize the concentration, irradiation time and radiation power used in experiments.
کلیدواژه‌ها
Hyperthermia؛ Multiwalled Carbon Nanotubes؛ Nanoparticles؛ Near Infrared؛ Photothermal Therapy
مراجع
  1. Bode AM, Dong Z. Cancer prevention research—then and now. Nature Reviews Cancer. 2009;9:508-16. doi.org/10.1038/nrc2646. PubMed PMID: 19536108. PubMed PMCID: 2838238.
  2. Allen B. Systemic targeted alpha radiotherapy for cancer. J Biomed Phys Eng. 2013;3:67-80. PubMed PMID: 25505750. PubMed PMCID: 4204497.
  3. Begg AC, Stewart FA, Vens C. Strategies to improve radiotherapy with targeted drugs. Nat Rev Cancer. 2011;11:239-53. doi.org/10.1038/nrc3007. PubMed PMID: 21430696.
  4. Prasanna PG, Stone HB, Wong RS, Capala J, Bernhard EJ, Vikram B, et al. Normal tissue protection for improving radiotherapy: Where are the Gaps? Transl Cancer Res. 2012;1:35-48. PubMed PMID: 22866245. PubMed PMCID: 3411185.
  5. Cherukuri P, Glazer ES, Curley SA. Targeted hyperthermia using metal nanoparticles. Adv Drug Deliv Rev. 2010;62:339-45. doi.org/10.1016/j.addr.2009.11.006. PubMed PMID: 19909777. PubMed PMCID: 2827640.
  6. Javidi M, Heydari M, Karimi A, Haghpanahi M, Navidbakhsh M, Razmkon A. Evaluation of the effects of injection velocity and different gel concentrations on nanoparticles in hyperthermia therapy. J Biomed Phys Eng. 2014;4:151-62. PubMed PMID: 25599061. PubMed PMCID: 4289522.
  7. Ghosh S, Dutta S, Gomes E, Carroll D, D’Agostino R, Jr., Olson J, et al. Increased heating efficiency and selective thermal ablation of malignant tissue with DNA-encased multiwalled carbon nanotubes. ACS Nano. 2009;3:2667-73. doi.org/10.1021/nn900368b. PubMed PMID: 19655728. PubMed PMCID: 2748720.
  8. Kremkau FW. Cancer therapy with ultrasound: a historical review. J Clin Ultrasound. 1979;7:287-300. doi.org/10.1002/jcu.1870070410. PubMed PMID: 112118.
  9. Cebrian V, Martin-Saavedra F, Gomez L, Arruebo M, Santamaria J, Vilaboa N. Enhancing of plasmonic photothermal therapy through heat-inducible transgene activity. Nanomedicine. 2013;9:646-56. doi.org/10.1016/j.nano.2012.11.002. PubMed PMID: 23178286.
  10. Day ES, Thompson PA, Zhang L, Lewinski NA, Ahmed N, Drezek RA, et al. Nanoshell-mediated photothermal therapy improves survival in a murine glioma model. J Neurooncol. 2011;104:55-63. doi.org/10.1007/s11060-010-0470-8. PubMed PMID: 21110217. PubMed PMCID: 3710584.
  11. Huang X, El-Sayed MA. Plasmonic photo-thermal therapy (PPTT). Alexandria Journal of Medicine. 2011;47:1-9. doi.org/10.1016/j.ajme.2011.01.001.
  12. Jin H, Yang P, Cai J, Wang J, Liu M. Photothermal effects of folate-conjugated Au nanorods on HepG2 cells. Appl Microbiol Biotechnol. 2012;94:1199-208. doi.org/10.1007/s00253-012-3935-1. PubMed PMID: 22406860.
  13. Leung JP, Wu S, Chou KC, Signorell R. Investigation of sub-100 nm gold nanoparticles for laser-induced thermotherapy of cancer. Nanomaterials. 2013;3:86-106. doi.org/10.3390/nano3010086.
  14. Young JK, Figueroa ER, Drezek RA. Tunable nanostructures as photothermal theranostic agents. Ann Biomed Eng. 2012;40:438-59. doi.org/10.1007/s10439-011-0472-5. PubMed PMID: 22134466.
  15. Diederich CJ, Hynynen K. Ultrasound technology for hyperthermia. Ultrasound in medicine & biology. 1999;25:871-87. doi.org/10.1016/S0301-5629(99)00048-4.
  16. Huang X, Jain PK, El-Sayed IH, El-Sayed MA. Plasmonic photothermal therapy (PPTT) using gold nanoparticles. Lasers Med Sci. 2008;23:217-28. doi.org/10.1007/s10103-007-0470-x. PubMed PMID: 17674122.
  17. C SR, Kumar J, V R, M V, Abraham A. Laser immunotherapy with gold nanorods causes selective killing of tumour cells. Pharmacol Res. 2012;65:261-9. doi.org/10.1016/j.phrs.2011.10.005. PubMed PMID: 22115972.
  18. Sirotkina M, Elagin V, Subochev P, Denisov N, Shirmanova M, Zagainova E. Laser hyperthermia of tumors using gold nanoparticles monitored by optical coherence tomography and acoustic thermometry. Biophysics. 2011;56:1102-5. doi.org/10.1134/S0006350911060194.
  19. Wu SY-H, Yang K-C, Tseng C-L, Chen J-C, Lin F-H. Silica-modified Fe-doped calcium sulfide nanoparticles for in vitro and in vivo cancer hyperthermia. Journal of Nanoparticle Research. 2011;13:1139-49. doi.org/10.1007/s11051-010-0106-0.
  20. Wust P, Hildebrandt B, Sreenivasa G, Rau B, Gellermann J, Riess H, et al. Hyperthermia in combined treatment of cancer. Lancet Oncol. 2002;3:487-97. doi.org/10.1016/S1470-2045(02)00818-5. PubMed PMID: 12147435.
  21. Burke A, Ding X, Singh R, Kraft RA, Levi-Polyachenko N, Rylander MN, et al. Long-term survival following a single treatment of kidney tumors with multiwalled carbon nanotubes and near-infrared radiation. Proc Natl Acad Sci U S A. 2009;106:12897-902. doi.org/10.1073/pnas.0905195106. PubMed PMID: 19620717. PubMed PMCID: 2722274.
  22. Fisher JW, Sarkar S, Buchanan CF, Szot CS, Whitney J, Hatcher HC, et al. Photothermal response of human and murine cancer cells to multiwalled carbon nanotubes after laser irradiation. Cancer Res. 2010;70:9855-64. doi.org/10.1158/0008-5472.CAN-10-0250. PubMed PMID: 21098701. PubMed PMCID: 3699181.
  23. Markovic ZM, Harhaji-Trajkovic LM, Todorovic-Markovic BM, Kepic DP, Arsikin KM, Jovanovic SP, et al. In vitro comparison of the photothermal anticancer activity of graphene nanoparticles and carbon nanotubes. Biomaterials. 2011;32:1121-9. doi.org/10.1016/j.biomaterials.2010.10.030. PubMed PMID: 21071083.
  24. Belin T, Epron F. Characterization methods of carbon nanotubes: a review. Materials Science and Engineering: B. 2005;119:105-18. doi.org/10.1016/j.mseb.2005.02.046.
  25. De Volder MF, Tawfick SH, Baughman RH, Hart AJ. Carbon nanotubes: present and future commercial applications. Science. 2013;339:535-9. doi.org/10.1126/science.1222453. PubMed PMID: 23372006.
  26. Trojanowicz M. Analytical applications of carbon nanotubes: a review. TrAC trends in analytical chemistry. 2006;25:480-9. doi.org/10.1016/j.trac.2005.11.008.
  27. Vairavapandian D, Vichchulada P, Lay MD. Preparation and modification of carbon nanotubes: review of recent advances and applications in catalysis and sensing. Anal Chim Acta. 2008;626:119-29. doi.org/10.1016/j.aca.2008.07.052. PubMed PMID: 18790113.
  28. Zhou F, Xing D, Ou Z, Wu B, Resasco DE, Chen WR. Cancer photothermal therapy in the near-infrared region by using single-walled carbon nanotubes. J Biomed Opt. 2009;14:021009. doi.org/10.1117/1.3078803. PubMed PMID: 19405722.
  29. Yu JG, Jiao FP, Chen XQ, Jiang XY, Peng ZG, Zeng DM, et al. Irradiation-mediated carbon nanotubes’ use in cancer therapy. J Cancer Res Ther. 2012;8:348-54. doi.org/10.4103/0973-1482.103511. PubMed PMID: 23174713.
  30. Shi Y, Ren L, Li D, Gao H, Yang B. Optimization conditions for single-walled carbon nanotubes dispersion. 2013.
  31. Habash RW, Bansal R, Krewski D, Alhafid HT. Thermal therapy, part 1: an introduction to thermal therapy. Crit Rev Biomed Eng. 2006;34:459-89. doi.org/10.1615/CritRevBiomedEng.v34.i6.20. PubMed PMID: 17725479.
آمار
تعداد مشاهده مقاله: 801
تعداد دریافت فایل اصل مقاله: 135


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب