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Effect of Tissue Composition on Dose Distribution in Electron Beam Radiotherapy | ||
| Journal of Biomedical Physics and Engineering | ||
| مقاله 3، دوره 5، شماره 1، خرداد 2015 اصل مقاله (499.89 K) | ||
| نوع مقاله: Original Research | ||
| نویسندگان | ||
| M Ghorbani1؛ Z S Tabatabaei* 1؛ A Vejdani Noghreiyan1؛ H Vosoughi1؛ C Knaup2 | ||
| 1Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 2Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, USA | ||
| چکیده | ||
| Objective: The aim of this study is to evaluate the effect of tissue composition on dose distribution in electron beam radiotherapy.Methods: A Siemens Primus linear accelerator and a phantom were simulated using MCNPX Monte Carlo code. In a homogeneous cylindrical phantom, six types of soft tissue and three types of tissue-equivalent materials were investigated. The tissues included muscle (skeletal), adipose tissue, blood (whole), breast tissue, soft tissue (9-components) and soft tissue (4-component). The tissue-equivalent materials were water, A-150 tissue-equivalent plastic and perspex. Electron dose relative to dose in 9-component soft tissue at various depths on the beam’s central axis was determined for 8, 12, and 14 MeV electron energies.Results: The results of relative electron dose in various materials relative to dose in 9-component soft tissue were reported for 8, 12 and 14 MeV electron beams as tabulated data. While differences were observed between dose distributions in various soft tissues and tissue-equivalent materials, which vary with the composition of material, electron energy and depth in phantom, they can be ignored due to the incorporated uncertainties in Monte Carlo calculations. Conclusion: Based on the calculations performed, differences in dose distributions in various soft tissues and tissue-equivalent materials are not significant. However, due to the difference in composition of various materials, further research in this field with lower uncertainties is recommended. | ||
| کلیدواژهها | ||
| Electron Mode؛ Linear accelerator؛ Monte Carlo Simulation؛ Soft tissue؛ Tissue-equivalent Materials | ||
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آمار تعداد مشاهده مقاله: 581 تعداد دریافت فایل اصل مقاله: 172 |
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