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Hadadi, Mahtab, Malekzadegan, Yalda, Heidari, Hamid, Sedigh Ebrahim-Saraie, Hadi, Motamedifar, Mohammad. (1395). Antimicrobial Resistance Pattern in Escherichia coli Isolates Obtained from a Specialized Women and Children Hospital in Shiraz, Iran: A Prevalence Study. سامانه مدیریت نشریات علمی, 4(4), 194-198.
Mahtab Hadadi; Yalda Malekzadegan; Hamid Heidari; Hadi Sedigh Ebrahim-Saraie; Mohammad Motamedifar. "Antimicrobial Resistance Pattern in Escherichia coli Isolates Obtained from a Specialized Women and Children Hospital in Shiraz, Iran: A Prevalence Study". سامانه مدیریت نشریات علمی, 4, 4, 1395, 194-198.
Hadadi, Mahtab, Malekzadegan, Yalda, Heidari, Hamid, Sedigh Ebrahim-Saraie, Hadi, Motamedifar, Mohammad. (1395). 'Antimicrobial Resistance Pattern in Escherichia coli Isolates Obtained from a Specialized Women and Children Hospital in Shiraz, Iran: A Prevalence Study', سامانه مدیریت نشریات علمی, 4(4), pp. 194-198.
Hadadi, Mahtab, Malekzadegan, Yalda, Heidari, Hamid, Sedigh Ebrahim-Saraie, Hadi, Motamedifar, Mohammad. Antimicrobial Resistance Pattern in Escherichia coli Isolates Obtained from a Specialized Women and Children Hospital in Shiraz, Iran: A Prevalence Study. سامانه مدیریت نشریات علمی, 1395; 4(4): 194-198.

Antimicrobial Resistance Pattern in Escherichia coli Isolates Obtained from a Specialized Women and Children Hospital in Shiraz, Iran: A Prevalence Study

Journal of Health Sciences & Surveillance System
مقاله 6، دوره 4، شماره 4، دی 2016، صفحه 194-198    اصل مقاله (293.8 K)
نوع مقاله: Original Articles
نویسندگان
Mahtab Hadadi1؛ Yalda Malekzadegan1؛ Hamid Heidari1؛ Hadi Sedigh Ebrahim-Saraie* 1؛ Mohammad Motamedifar2
1Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Shiraz HIV/AIDS Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
AbstractBackground: Escherichia coli, known as a clinically significantbacteria, can cause a wide range of infections, including urinarytract infections (UTIs), blood stream infections (BSIs), andcan frequently be isolated from various clinical specimens.Evaluation of antimicrobial resistant pattern is a necessaryaction, especially about such bacteria which are frequent andlife threatening. The aim of this study was to determine thefrequency and antimicrobial resistance pattern of E. coli isolatesobtained from various clinical specimens.Methods: This retrospective study was performed within a sevenmonth period from January 2015 to August 2015 at a specializedwomen and children hospital in Shiraz, Iran. E. coli isolates wereobtained from various clinical specimens and identified usingstandard microbiological procedure. Antimicrobial susceptibilitypatterns were determined using disk diffusion method inaccordance with CLSI recommendation.Results: Of the total 130 positive cultures, the majority of E.coli isolates were obtained from urine (96=73.8%) and blood(11=8.5%) specimens. Overall, gentamicin (70.8%) was theeffective antibiotic for the tested E. coli isolates. E. coli isolatesobtained from urine specimens showed the highest resistancerates against ampicillin (84.4%) and nalidixic acid (61.5%);while they showed the most sensitivity to gentamicin (79.2%),nitrofurantoin (70.8%) and ciprofloxacin (66.7%). Moreover,the highest antibiotic resistance rates belonged to the isolatesrecovered from endotracheal tube (ETT).Conclusion: The results showed that gentamicin was the mosteffective antibiotic against E. coli infections. However, inaddition to the gentamicin, we can recommend nitrofurantoinand ciprofloxacin as the other effective agents for UTIs.
کلیدواژه‌ها
Escherichia coli؛ women؛ children؛ Nosocomial infections؛ Antibiotic susceptibility
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