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Vakili, Bahareh, Mokarram, Pooneh. (1395). DNA-Directed Methylation Analysis Methodology. سامانه مدیریت نشریات علمی, 2(2), 220-223. doi: 10.18869/nrip.jamsat.2.2.220
Bahareh Vakili; Pooneh Mokarram. "DNA-Directed Methylation Analysis Methodology". سامانه مدیریت نشریات علمی, 2, 2, 1395, 220-223. doi: 10.18869/nrip.jamsat.2.2.220
Vakili, Bahareh, Mokarram, Pooneh. (1395). 'DNA-Directed Methylation Analysis Methodology', سامانه مدیریت نشریات علمی, 2(2), pp. 220-223. doi: 10.18869/nrip.jamsat.2.2.220
Vakili, Bahareh, Mokarram, Pooneh. DNA-Directed Methylation Analysis Methodology. سامانه مدیریت نشریات علمی, 1395; 2(2): 220-223. doi: 10.18869/nrip.jamsat.2.2.220

DNA-Directed Methylation Analysis Methodology

Journal of Advanced Medical Sciences and Applied Technologies
مقاله 5، دوره 2، شماره 2، شهریور 2016، صفحه 220-223    اصل مقاله (517.88 K)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.18869/nrip.jamsat.2.2.220
نویسندگان
Bahareh Vakili؛ Pooneh Mokarram*
چکیده
Epigenetics alterations, especially DNA methylation, play a critical role in control of gene expressions. Abnormal patterns of methylation are observed in early-stages of many cancers. Therefore, methylation analysis is useful in primary detection of tumors. Advances knowledge about the functional role of aberrant epigenetic modifications as potential biomarkers for cancer, have attracted considerable interest to pursue such investigations. Currently, many methodologies are available to distinguish methylation patterns, however, none is considered as the ‘gold-standard’ technique. This paper is an overview on some convenient methylation analysis methods.
کلیدواژه‌ها
DNA methylation؛ Bisulfite؛ High-throughput؛ Quantitative methylation؛ Microarray
مراجع
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