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Tfayli, Arafat, Attarian, Hamid, Ghadyani, Mojtaba, Ghotb, Atabak, Mashadian, Mehrdad, Salimi, Babak, Sedaghat, Sadegh, Seghatoleslami, Mohammad, Seifi, Sharareh, Torabi-Nami, Mohammad. (1394). Immunotherapy in Metastatic Malignant Melanoma and Non-Small Cell Lung Cancer; a Brief Review and Position Statement from the Immuno-Oncology Clinical Forum (IOCF), Iran. سامانه مدیریت نشریات علمی, 2(1), 190-196. doi: 10.18869/nrip.jamsat.2.1.190
Arafat Tfayli; Hamid Attarian; Mojtaba Ghadyani; Atabak Ghotb; Mehrdad Mashadian; Babak Salimi; Sadegh Sedaghat; Mohammad Seghatoleslami; Sharareh Seifi; Mohammad Torabi-Nami. "Immunotherapy in Metastatic Malignant Melanoma and Non-Small Cell Lung Cancer; a Brief Review and Position Statement from the Immuno-Oncology Clinical Forum (IOCF), Iran". سامانه مدیریت نشریات علمی, 2, 1, 1394, 190-196. doi: 10.18869/nrip.jamsat.2.1.190
Tfayli, Arafat, Attarian, Hamid, Ghadyani, Mojtaba, Ghotb, Atabak, Mashadian, Mehrdad, Salimi, Babak, Sedaghat, Sadegh, Seghatoleslami, Mohammad, Seifi, Sharareh, Torabi-Nami, Mohammad. (1394). 'Immunotherapy in Metastatic Malignant Melanoma and Non-Small Cell Lung Cancer; a Brief Review and Position Statement from the Immuno-Oncology Clinical Forum (IOCF), Iran', سامانه مدیریت نشریات علمی, 2(1), pp. 190-196. doi: 10.18869/nrip.jamsat.2.1.190
Tfayli, Arafat, Attarian, Hamid, Ghadyani, Mojtaba, Ghotb, Atabak, Mashadian, Mehrdad, Salimi, Babak, Sedaghat, Sadegh, Seghatoleslami, Mohammad, Seifi, Sharareh, Torabi-Nami, Mohammad. Immunotherapy in Metastatic Malignant Melanoma and Non-Small Cell Lung Cancer; a Brief Review and Position Statement from the Immuno-Oncology Clinical Forum (IOCF), Iran. سامانه مدیریت نشریات علمی, 1394; 2(1): 190-196. doi: 10.18869/nrip.jamsat.2.1.190

Immunotherapy in Metastatic Malignant Melanoma and Non-Small Cell Lung Cancer; a Brief Review and Position Statement from the Immuno-Oncology Clinical Forum (IOCF), Iran

Journal of Advanced Medical Sciences and Applied Technologies
مقاله 8، دوره 2، شماره 1، خرداد 2016، صفحه 190-196    اصل مقاله (527.55 K)
نوع مقاله: Brief Report
شناسه دیجیتال (DOI): 10.18869/nrip.jamsat.2.1.190
نویسندگان
Arafat Tfayli1؛ Hamid Attarian2؛ Mojtaba Ghadyani2؛ Atabak Ghotb3؛ Mehrdad Mashadian4؛ Babak Salimi2؛ Sadegh Sedaghat5؛ Mohammad Seghatoleslami6؛ Sharareh Seifi2؛ Mohammad Torabi-Nami* 7
1NK Basile Cancer Institute, American University of Beirut Medical Center, Beirut
2Department of Hematology-Oncology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3Behphar Scientific Committee, Behphar Group, Tehran, Iran
4Hematology-Oncology Division, Atieh Hospital, Tehran, Iran
5Department of Hematology-Oncology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
6Department of Hematology-Oncology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
7Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Given the unmet needs in cancer treatment, extensive research and development has evolved to offer therapies for cancers to extend survival and minimize side effects. Immunotherapy, an approach to harness normal immune cells against cancers not only today’s breakthrough but in fact the future of oncology therapeutics. Taking into consideration the recent approvals for new lines of therapy including anti-programmed-death-1 or programmed-death-1 ligand (PD-1/PD-L1) monoclonal antibodies for the treatment of Malignant Melanoma (MM) and Non-Small Cell Lung Cancer (NSCLC), local strategies need to be established following the field experts’ concurrence. Expert input forums are among the key approaches to define locally-adapted clinical-pathways with regard to the novel treatments. To this end, a panel of Iranian medical oncology experts reviewed the available evidence, taking into consideration recent practice guidelines with regard to the treatment of MM and NSCLC in order to draw an agreed-upon approach highlighting the position of immunotherapy in their current practice. Having addressed the key questions and considering the possible limitations and challenges, the panel could reach an agreed position. This report highlights the discussions with regards to the role of immunotherapy in MM and NSCLC during the immune-oncology clinical forum (IOCF) comprising an Iranian panel of experts.
کلیدواژه‌ها
Immunotherapy؛ Malignant melanoma؛ NSCLC؛ PD-1/PDL-1؛ Oncology؛ Iran
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