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Farhadi, Tayebeh, Karimi, Zeinab, Ghasemi, Younes, Nezafat, Navid, Hemmati, Shiva, Erfani, Nasrollah. (1394). Production of a novel multi-epitope vaccine based on outer membrane proteins of Klebsiella pneumoniae. سامانه مدیریت نشریات علمی, 1(3), 167-172.
Tayebeh Farhadi; Zeinab Karimi; Younes Ghasemi; Navid Nezafat; Shiva Hemmati; Nasrollah Erfani. "Production of a novel multi-epitope vaccine based on outer membrane proteins of Klebsiella pneumoniae". سامانه مدیریت نشریات علمی, 1, 3, 1394, 167-172.
Farhadi, Tayebeh, Karimi, Zeinab, Ghasemi, Younes, Nezafat, Navid, Hemmati, Shiva, Erfani, Nasrollah. (1394). 'Production of a novel multi-epitope vaccine based on outer membrane proteins of Klebsiella pneumoniae', سامانه مدیریت نشریات علمی, 1(3), pp. 167-172.
Farhadi, Tayebeh, Karimi, Zeinab, Ghasemi, Younes, Nezafat, Navid, Hemmati, Shiva, Erfani, Nasrollah. Production of a novel multi-epitope vaccine based on outer membrane proteins of Klebsiella pneumoniae. سامانه مدیریت نشریات علمی, 1394; 1(3): 167-172.

Production of a novel multi-epitope vaccine based on outer membrane proteins of Klebsiella pneumoniae

Trends in Pharmaceutical Sciences
مقاله 7، دوره 1، شماره 3، آذر 2015، صفحه 167-172    اصل مقاله (376.97 K)
نوع مقاله: Research(Original) Article
نویسندگان
Tayebeh Farhadi؛ Zeinab Karimi؛ Younes Ghasemi* ؛ Navid Nezafat؛ Shiva Hemmati؛ Nasrollah Erfani
چکیده
Klebsiella pneumoniae is a hospital-acquired pathogen that leads to various infections. Hence, efforts to develop an effective vaccine against that pathogen are well documented. Our interest is the production of the previously designed multi-epitope vaccine construct against the K. pneumoniae in a prokaryotic host. Therefore, a new construct containing the nucleotide sequence of the novel vaccine was successfully expressed in Escherichia coli and then purified by Ni-NTA spin column. The purified recombinant protein can be considered as potential vaccine candidate for wet-laboratory analysis aiming to fight K pneumoniae .
کلیدواژه‌ها
Klebsiella pneumoniae؛ multi-epitope vaccine؛ production
مراجع
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