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Mahmoud, Hemat, Atta, Haisam, Diab, Waleed, Eloteify, Lamiaa, Mourad, Abd Elmonem, Gabr, Adel, Mekkawy, Mohamed, Omar, Waleed. (1395). The Debate on Pelvic Lymphadenopathy Size Significance in Ovarian Cancer Patients. سامانه مدیریت نشریات علمی, 7(2), 85-91.
Hemat A. Mahmoud; Haisam Atta; Waleed A. Diab; Lamiaa M. Eloteify; Abd Elmonem Mourad; Adel Gabr; Mohamed A. Mekkawy; Waleed M. Omar. "The Debate on Pelvic Lymphadenopathy Size Significance in Ovarian Cancer Patients". سامانه مدیریت نشریات علمی, 7, 2, 1395, 85-91.
Mahmoud, Hemat, Atta, Haisam, Diab, Waleed, Eloteify, Lamiaa, Mourad, Abd Elmonem, Gabr, Adel, Mekkawy, Mohamed, Omar, Waleed. (1395). 'The Debate on Pelvic Lymphadenopathy Size Significance in Ovarian Cancer Patients', سامانه مدیریت نشریات علمی, 7(2), pp. 85-91.
Mahmoud, Hemat, Atta, Haisam, Diab, Waleed, Eloteify, Lamiaa, Mourad, Abd Elmonem, Gabr, Adel, Mekkawy, Mohamed, Omar, Waleed. The Debate on Pelvic Lymphadenopathy Size Significance in Ovarian Cancer Patients. سامانه مدیریت نشریات علمی, 1395; 7(2): 85-91.

The Debate on Pelvic Lymphadenopathy Size Significance in Ovarian Cancer Patients

Middle East Journal of Cancer
مقاله 3، دوره 7، شماره 2، تیر 2016، صفحه 85-91    اصل مقاله (3.3 M)
نوع مقاله: Original Article(s)
نویسندگان
Hemat A. Mahmoud1؛ Haisam Atta* 2؛ Waleed A. Diab1؛ Lamiaa M. Eloteify1؛ Abd Elmonem Mourad3؛ Adel Gabr4؛ Mohamed A. Mekkawy1؛ Waleed M. Omar5
1Department of Clinical Oncology and Nuclear Medicine, Assiut University Hospital, Assiut, Egypt
2Department of Radiology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt
3Department of Radiology, Assiut University Hospital, Assiut, Egypt
4Department of Medical Oncology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt
5Department of Nuclear Medicine, National Cancer Institute, Cairo University, Cairo, Egypt
چکیده
Background: This study attempts to ascertain a reliable cutoff size to determine whether pelvic lymph nodes are metastatic or not in ovarian cancer patients.Methods: We retrospectively reviewed 73 PET/CT scans of 52 female patients with ovarian carcinoma who underwent surgery followed by chemotherapy. The findings of contrast enhanced MDCT were interpreted by two experienced radiologists unaware of the PET/CT findings. At least two experienced nuclear medicine physicians unaware of the contrast enhanced-MDCT findings examined the PET scans in order to localize, characterize and compare these scans to co-registered PET/CT images. A comparative study was done. Lymph node sizes were recorded in short axis diameter with a significant cut off estimated at 7.5 mm. Metabolic activities of different lymph node groups were assessed and the semi-quantitative SUV was calculated. The level of SUV significance was 2.5. Significant metastatic lymph nodes were judged by the assessment of integrated PET/CT results.Results: Of the 73 scans, 47 showed significant lymph node metastases, with the following sensitivities: 75% (external iliac), 77.8% (internal iliac), and 75% (inguinal). The specificities were 84% (external iliac), 86% (internal iliac), and 54% (inguinal) with a P-value of 0.000 for the external an internal iliac groups and 0.079 for the inguinal group.Conclusion: To improve detection of malignant pelvic lymph nodes, the size threshold should be decreased to 7.5 mm.
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