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Khademi, Bijan, Bahranifard, Hajar, Kabiri, Sayed Hamed, Razzaghi, Samiraz, Hashemi, Seyed Basir, Shishegar, Mahmood, Mohammadianpanah, Mohammad. (1390). Nasopharyngeal Adenoid Cystic Carcinoma: Report of Five Cases and Treatment Outcome. سامانه مدیریت نشریات علمی, 2(2), 81-85.
Bijan Khademi; Hajar Bahranifard; Sayed Hamed Kabiri; Samiraz Razzaghi; Seyed Basir Hashemi; Mahmood Shishegar; Mohammad Mohammadianpanah. "Nasopharyngeal Adenoid Cystic Carcinoma: Report of Five Cases and Treatment Outcome". سامانه مدیریت نشریات علمی, 2, 2, 1390, 81-85.
Khademi, Bijan, Bahranifard, Hajar, Kabiri, Sayed Hamed, Razzaghi, Samiraz, Hashemi, Seyed Basir, Shishegar, Mahmood, Mohammadianpanah, Mohammad. (1390). 'Nasopharyngeal Adenoid Cystic Carcinoma: Report of Five Cases and Treatment Outcome', سامانه مدیریت نشریات علمی, 2(2), pp. 81-85.
Khademi, Bijan, Bahranifard, Hajar, Kabiri, Sayed Hamed, Razzaghi, Samiraz, Hashemi, Seyed Basir, Shishegar, Mahmood, Mohammadianpanah, Mohammad. Nasopharyngeal Adenoid Cystic Carcinoma: Report of Five Cases and Treatment Outcome. سامانه مدیریت نشریات علمی, 1390; 2(2): 81-85.

Nasopharyngeal Adenoid Cystic Carcinoma: Report of Five Cases and Treatment Outcome

Middle East Journal of Cancer
مقاله 6، دوره 2، شماره 2، تیر 2011، صفحه 81-85    اصل مقاله (144.64 K)
نوع مقاله: Case Series
نویسندگان
Bijan Khademi1؛ Hajar Bahranifard2؛ Sayed Hamed Kabiri3؛ Samiraz Razzaghi4؛ Seyed Basir Hashemi2؛ Mahmood Shishegar2؛ Mohammad Mohammadianpanah* 5
1Cancer Research Center, Department of Otolaryngology, Head and Neck Surgery, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
2Department of Otolaryngology, Head and Neck Surgery, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
3Department of Surgery, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
4Department of Radiation Oncology, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
5Cancer Research Center, Department of Radiation Oncology, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: The present study aimed to report the characteristics and treatment outcomes of five patients with nasopharyngeal adenoid cystic carcinoma and a literature review.Methods: Between 2000 and 2009, five consecutive patients (4 men, 1 woman) were diagnosed with nasopharyngeal adenoid cystic carcinoma and treated at our institution. Three patients had stage IVa (T4N0M0) and two patients had stage III (T3N0M0) cancer. Primary treatment consisted of concurrent chemoradiation in three patients and radiotherapy alone in two patients. Surgery was limited to endoscopic biopsy for histological diagnosis.Results: Four patients achieved complete response during or after completion of treatment and remained free of disease for a median of 27 months. Four patients developed local recurrence 8-30 months after initial treatment. The fifth patient is alive and free of disease.Conclusion: The findings of the present study and literature review suggest that local failure is a major problem in adenoid cystic carcinoma of the nasopharynx.
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