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Dehghani, Mehdi, Karimi, Vahid Mohammad. (1391). Nephrogenic Diabetes Insipidus: A Rare Presentation in Multiple Myeloma. سامانه مدیریت نشریات علمی, 3(Issue 2-3), 89-92.
Mehdi Dehghani; Vahid Mohammad Karimi. "Nephrogenic Diabetes Insipidus: A Rare Presentation in Multiple Myeloma". سامانه مدیریت نشریات علمی, 3, Issue 2-3, 1391, 89-92.
Dehghani, Mehdi, Karimi, Vahid Mohammad. (1391). 'Nephrogenic Diabetes Insipidus: A Rare Presentation in Multiple Myeloma', سامانه مدیریت نشریات علمی, 3(Issue 2-3), pp. 89-92.
Dehghani, Mehdi, Karimi, Vahid Mohammad. Nephrogenic Diabetes Insipidus: A Rare Presentation in Multiple Myeloma. سامانه مدیریت نشریات علمی, 1391; 3(Issue 2-3): 89-92.

Nephrogenic Diabetes Insipidus: A Rare Presentation in Multiple Myeloma

Middle East Journal of Cancer
مقاله 9، دوره 3، Issue 2-3، مهر 2012، صفحه 89-92    اصل مقاله (261.99 K)
نوع مقاله: Case Report(s)
نویسندگان
Mehdi Dehghani* ؛ Vahid Mohammad Karimi
Shiraz University of Medical Sciences, Hematology Research Center, Shiraz, Iran
چکیده
We report a case of multiple myeloma that presented with anorexia, fatigue, high erythrocyte sedimentation rate, bone marrow plasmacytosis of more than 30%, polyuria,and low urine specific gravity. This unusual presentation was diagnosed as nephrogenic diabetes insipidus secondary to a proximal tubular dysfunction. The tubular functional disturbance appeared to be related to the presence of lambda-type light chains. The patient was treated with desmopressine without response. After one month of treatment with thalidomide and dexamethasone for myeloma there was a dramatic response with decreased urine output.
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