LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,093
تعداد مقالات10,030
تعداد مشاهده مقاله27,440,627
تعداد دریافت فایل اصل مقاله7,582,117
Heydari, Abbas, Sharifi, Hassan, Salek, Roham. (1391). Effect of Oral Cryotherapy on Combination Chemotherapy-induced Oral Mucositis: A Randomized Clinical Trial. سامانه مدیریت نشریات علمی, 3(Issue 2-3), 55-64.
Abbas Heydari; Hassan Sharifi; Roham Salek. "Effect of Oral Cryotherapy on Combination Chemotherapy-induced Oral Mucositis: A Randomized Clinical Trial". سامانه مدیریت نشریات علمی, 3, Issue 2-3, 1391, 55-64.
Heydari, Abbas, Sharifi, Hassan, Salek, Roham. (1391). 'Effect of Oral Cryotherapy on Combination Chemotherapy-induced Oral Mucositis: A Randomized Clinical Trial', سامانه مدیریت نشریات علمی, 3(Issue 2-3), pp. 55-64.
Heydari, Abbas, Sharifi, Hassan, Salek, Roham. Effect of Oral Cryotherapy on Combination Chemotherapy-induced Oral Mucositis: A Randomized Clinical Trial. سامانه مدیریت نشریات علمی, 1391; 3(Issue 2-3): 55-64.

Effect of Oral Cryotherapy on Combination Chemotherapy-induced Oral Mucositis: A Randomized Clinical Trial

Middle East Journal of Cancer
مقاله 4، دوره 3، Issue 2-3، مهر 2012، صفحه 55-64    اصل مقاله (305.28 K)
نوع مقاله: Original Article(s)
نویسندگان
Abbas Heydari1؛ Hassan Sharifi* 2؛ Roham Salek3
1Department of Medical Surgical Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
2Department of Medical Surgical Nursing, Iranshahr School of Nursing and Midwifery, Zahedan University of Medical Sciences, Iranshahr, Iran
3Department of Oncology/Radiotherapy, Mashhad University of Medical Sciences, Mashhad, Iran
چکیده
Background: This study assesses the effect of oral cryotherapy on the incidence and severity of chemotherapy-induced oral mucositis in combined chemotherapy regimens.Methods: This was a randomized controlled trial that enrolled 80 cancer patients. We evaluated the primary oral status of all patients prior to chemotherapy. Patients were divided into two groups, experimental and control. The experimental group was given ice to place in their mouths from 5 min before to 5 min after chemotherapy.The control group received no intervention. Both groups were treated with the following chemotherapy regimens: i) 5- fluorouracil + leucovorin; ii) cyclophosphamide + adriamycin + 5-fluorouracil; or iii) cyclophosphamide + methotrexate + fluorouracil. World Health Organization and patient-based oral mucositis scales were used for evaluation.Results: According to the WHO based Oral Mucositis Scale, the incidence of oral mucositis in the intervention group (45%) was significantly lower than the control group (77.5%; P=0.01). The incidence of oral mucositis in the intervention group based on the Patient-Judged Oral Mucositis Scale was lower than the control group. The findings of this study indicated that patients who underwent cryotherapy had less severe oral mucositis based on both WHO (P=0.01) and patient oral mucositis scales (P=0.001).Conclusion: Oral cryotherapy because of its ease of application, tolerability and lack of side effects makes it an important resource for reducing the incidence and severity of oral mucositis. The role of oncology nurses is crucial to the application and success of oral cryotherapy.
آمار
تعداد مشاهده مقاله: 5,601
تعداد دریافت فایل اصل مقاله: 1,072


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب