تعداد نشریات | 20 |
تعداد شمارهها | 1,149 |
تعداد مقالات | 10,518 |
تعداد مشاهده مقاله | 45,416,258 |
تعداد دریافت فایل اصل مقاله | 11,292,113 |
Postoperative Pain Management after Impacted Third Molar Surgery with Preoperative Oral Lamotrigine, a Randomized, Double-blind, Placebo-Controlled Trial | ||
Journal of Dentistry | ||
مقاله 4، دوره 19، شماره 3، آذر 2018، صفحه 189-196 اصل مقاله (243.75 K) | ||
نوع مقاله: Original Article | ||
شناسه دیجیتال (DOI): 10.30476/dentjods.2018.41811 | ||
نویسندگان | ||
Hamed Modanloo1؛ Hamıdreza Eftekharıan* 2؛ Hamidreza Arabiun2 | ||
1Postgraduate Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. | ||
2Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. | ||
چکیده | ||
Statement of the Problem: Extraction of the impacted third molar is often associated with severe postoperative pains, management of which are a big challenge. Lamotrigine is a new antiepileptic drug with pre-emptive analgesic properties, which is hypothesized to alleviate postoperative pain.Purpose: This study aimed to evaluate the efficacy of pre-operative administration of single oral 200 mg lamotrigine in reducing the postoperative pain of impacted third molar surgery.Materials and Method: In this randomized controlled trial, 100 adult patients were divided into two groups (n= 50) to receive either 200 mg oral lamotrigine or placebo 1 hour before the removal of impacted third molar. The patients were monitored for 4 hours in the recovery room and pain intensity was measured through visual analogue scale (VAS) for the next 12 hours at 30-minute intervals. The time and number of rescue analgesics used in 12 hours was also recorded.Results: Two groups were not statistically significantly different regarding the severity of postoperative pain. (p= 0.512)Conclusion: Accordingly, pre-emptive administration of lamotrigine was not effective in diminishing the postoperative acute pain of impacted third molar extraction.Key Words Lamotrigine; Third Molar; Pain Management; | ||
آمار تعداد مشاهده مقاله: 870 تعداد دریافت فایل اصل مقاله: 427 |