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Zanwar, Kushal, Kumar Ganji, Kiran, Bhongade, Manohar L. (1396). Efficacy of Human Umbilical Stem Cells Cultured on Polylactic/ Polyglycolic Acid Membrane in the Treatment of Multiple Gingival Recession Defects: a Randomized Controlled Clinical Study. سامانه مدیریت نشریات علمی, 18(2), 95-103.
Kushal Zanwar; Kiran Kumar Ganji; Manohar L Bhongade. "Efficacy of Human Umbilical Stem Cells Cultured on Polylactic/ Polyglycolic Acid Membrane in the Treatment of Multiple Gingival Recession Defects: a Randomized Controlled Clinical Study". سامانه مدیریت نشریات علمی, 18, 2, 1396, 95-103.
Zanwar, Kushal, Kumar Ganji, Kiran, Bhongade, Manohar L. (1396). 'Efficacy of Human Umbilical Stem Cells Cultured on Polylactic/ Polyglycolic Acid Membrane in the Treatment of Multiple Gingival Recession Defects: a Randomized Controlled Clinical Study', سامانه مدیریت نشریات علمی, 18(2), pp. 95-103.
Zanwar, Kushal, Kumar Ganji, Kiran, Bhongade, Manohar L. Efficacy of Human Umbilical Stem Cells Cultured on Polylactic/ Polyglycolic Acid Membrane in the Treatment of Multiple Gingival Recession Defects: a Randomized Controlled Clinical Study. سامانه مدیریت نشریات علمی, 1396; 18(2): 95-103.

Efficacy of Human Umbilical Stem Cells Cultured on Polylactic/ Polyglycolic Acid Membrane in the Treatment of Multiple Gingival Recession Defects: a Randomized Controlled Clinical Study

Journal of Dentistry
مقاله 4، دوره 18، شماره 2، شهریور 2017، صفحه 95-103    اصل مقاله (618.86 K)
نوع مقاله: Original Article
نویسندگان
Kushal Zanwar1؛ Kiran Kumar Ganji* 2؛ Manohar L Bhongade1
1Dept. of Periodontics, Sharad Pawar Dental College, Wardha, India Affifilated to Datta Meghe Institute of Medical Sciences, Nagpur, India.
2Dept. of Periodontics, College of Dentistry, Sakaka Affifilated to Aljouf University, Aljouf Province, KSA.
چکیده
Statement of the Problem: Recently allogenic mesenchymal stem cells are proposed to have multipotential progenitor cell capabilities to differentiate into cementoblasts, osteoblasts, and periodontal ligament fibroblasts.Purpose: The aim of the present study was to compare the efficacy of human umbilical stem cells cultured on polylactic acid (PLA), polyglycolic acid (PGA) membrane with PLA/PGA membrane alone in the treatment of multiple gingival recession defects.Materials and Method: A total number of 14 cases of multiple gingival recession (Miller’s Class I or II) located in the anterior region were randomly selected and divided into test (stem cells in combination with PLA/PGA membrane) and control group (PLA/PGA membrane alone). Clinical parameters including gingival recession, probing pocket depth, clinical attachment level, and width of keratinized gingiva were recorded at baseline, and at 6 months postoperative.Results: At baseline, there was 2.28 mm and 2.14mm mean gingival recession at 16 sites and 14 sites in test and control groups respectively. At 6 months post-surgery, test group showed 1.57 mm mean reduction of gingival recession indicating 66% root coverage, while the control group showed 1.24mm mean reduction of gingival recession indicating 57% root coverage.Conclusion: In the present study, the stem cell with PLA/PGA membrane showed significantly higher mean root coverage compared to only PLA/PGA membrane group. Keywords  ● PLA/PGA membrane  ● Stem cells  ● Gingival recession
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