LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,149
تعداد مقالات10,518
تعداد مشاهده مقاله45,415,890
تعداد دریافت فایل اصل مقاله11,291,540
Gholizadeh, N., Mehdipour, M., Najafi, Sh., Bahramian, A., Garjani, Sh., Khoeini Poorfar, H.. (1393). Evaluation of the Serum Zinc Level in Erosive and Non-Erosive Oral Lichen Planus. سامانه مدیریت نشریات علمی, 15(2), 52-56.
N. Gholizadeh; M. Mehdipour; Sh. Najafi; A. Bahramian; Sh. Garjani; H. Khoeini Poorfar. "Evaluation of the Serum Zinc Level in Erosive and Non-Erosive Oral Lichen Planus". سامانه مدیریت نشریات علمی, 15, 2, 1393, 52-56.
Gholizadeh, N., Mehdipour, M., Najafi, Sh., Bahramian, A., Garjani, Sh., Khoeini Poorfar, H.. (1393). 'Evaluation of the Serum Zinc Level in Erosive and Non-Erosive Oral Lichen Planus', سامانه مدیریت نشریات علمی, 15(2), pp. 52-56.
Gholizadeh, N., Mehdipour, M., Najafi, Sh., Bahramian, A., Garjani, Sh., Khoeini Poorfar, H.. Evaluation of the Serum Zinc Level in Erosive and Non-Erosive Oral Lichen Planus. سامانه مدیریت نشریات علمی, 1393; 15(2): 52-56.

Evaluation of the Serum Zinc Level in Erosive and Non-Erosive Oral Lichen Planus

Journal of Dentistry
مقاله 2، دوره 15، شماره 2، شهریور 2014، صفحه 52-56    اصل مقاله (98.46 K)
نوع مقاله: Original Article
نویسندگان
N. Gholizadeh1؛ M. Mehdipour2؛ Sh. Najafi1؛ A. Bahramian3؛ Sh. Garjani4؛ H. Khoeini Poorfar* 5
1Dept. of Oral Medicine, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
2Dept. of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3Dept. of Oral Medicine, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
4Dept. of Oral Radiology, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
5Dept. of Pediatric Oncology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
چکیده
Statement of Problem: Lichen planus is a chronic inflammatory immunologic-based disease involving skin and mucosa. This disease is generally divided into two categories: erosive and non-erosive. Many etiologic factors are deliberated regarding the disease; however, the disorders of immune system and the role of cytotoxic T-lymphocytes and monocytes are more highlighted. Zinc is an imperative element for the growth of epithelium and its deficiency induces the cytotoxic activity of T-helper2 cells, which seems to be associated with lichen planus.Purpose: This study was aimed to evaluate the levels of serum zinc in erosive and non-erosive oral lichen planus (OLP) and to compare it with the healthy control group to find out any feasible inference.Materials and Method: A total of 22 patients with erosive oral lichen planus, 22 patients with non erosive OLP and 44 healthy individuals as the control group were recruited in this descriptive-comparative study. All the participants were selected from the referees to the department of oral medicine, school of dentistry, Tabriz University of Medical Sciences. Serum zinc level was examined for all the individuals with liquid-stat kit (Beckman Instruments Inc.; Carlsbad, CA). Data were analyzed by adopting the ANOVA and Tukey tests, using SPSS 16 statistical software.Results: The mean age of patients with erosive and non-erosive LP was 41.7 and 41.3 years, respectively. The mean age of the healthy control group was 34.4 years .The mean serum zinc levels in the erosive and non erosive lichen planus groups and control groups were 8.3 (1.15), 11.15 (0.92) and 15.74 (1.75) μg/dl respectively. The difference was statistically significant (p< 0.05).Conclusion: The serum zinc levels were decreased in patients with erosive oral lichen planus. This finding may probably indicate the promising role of zinc in development of oral lichen planus.Key Words: Lichen Planus; T helper; Zinc
آمار
تعداد مشاهده مقاله: 1,519
تعداد دریافت فایل اصل مقاله: 365


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب