LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,093
تعداد مقالات10,030
تعداد مشاهده مقاله27,418,293
تعداد دریافت فایل اصل مقاله7,570,328
Mahmoudi, Asghar, Gaeini, Abbasali. (1397). Interaction of Endurance Training and Low Calorie Diet on Homocysteine Levels and Lipid Profile of Plasma in Males with Non-Alcoholic Fatty Liver Disease. سامانه مدیریت نشریات علمی, 5(2), 46-52. doi: 10.30476/jrsr.2018.41138
Asghar Mahmoudi; Abbasali Gaeini. "Interaction of Endurance Training and Low Calorie Diet on Homocysteine Levels and Lipid Profile of Plasma in Males with Non-Alcoholic Fatty Liver Disease". سامانه مدیریت نشریات علمی, 5, 2, 1397, 46-52. doi: 10.30476/jrsr.2018.41138
Mahmoudi, Asghar, Gaeini, Abbasali. (1397). 'Interaction of Endurance Training and Low Calorie Diet on Homocysteine Levels and Lipid Profile of Plasma in Males with Non-Alcoholic Fatty Liver Disease', سامانه مدیریت نشریات علمی, 5(2), pp. 46-52. doi: 10.30476/jrsr.2018.41138
Mahmoudi, Asghar, Gaeini, Abbasali. Interaction of Endurance Training and Low Calorie Diet on Homocysteine Levels and Lipid Profile of Plasma in Males with Non-Alcoholic Fatty Liver Disease. سامانه مدیریت نشریات علمی, 1397; 5(2): 46-52. doi: 10.30476/jrsr.2018.41138

Interaction of Endurance Training and Low Calorie Diet on Homocysteine Levels and Lipid Profile of Plasma in Males with Non-Alcoholic Fatty Liver Disease

Journal of Rehabilitation Sciences & Research
مقاله 4، دوره 5، شماره 2، شهریور 2018، صفحه 46-52    اصل مقاله (778.29 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.30476/jrsr.2018.41138
نویسندگان
Asghar Mahmoudi* 1؛ Abbasali Gaeini2
1Department of Physical Education and Sport Sciences, Faculty of Education and Psychology, Univercity of Mohaghegh Ardabili, Ardabil, Iran.
2Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, University of Tehran, Tehran, Iran.
چکیده
Background: Lifestyle change through diet and exercise is first line therapy for non-alcoholic fatty liver disease (NAFLD), which is associated with increase in risk of cardiovascular disease. Therefore the aim of this study was to investigate the effect of endurance training and low calorie diet on levels of homocysteine and plasma lipid profiles in men with NAFLD. Methods: 70 patients with NAFLD [weight 89.6±5.8 , age 39.2±0.5 years, body mass index (BMI) 29.4±1.9 kg/m2] were randomly assigned into four groups(training, diet, combined of training & diet, and control). The endurance training program included moderate intensity training with 55-75% of maximal heart rate for 45 min/session, 3 times/week for 8 weeks. Low calorie diet with an energy deficit of 500 calories of daily energy intake was calculated from 3-day food records of the patients. Blood samples were measured before and after intervention. Homocysteine levels and lipid profiles were measured before and after intervention. Results: Fifty out of the 70 of the participants completed the trial. There were no serious adverse effects. Result exhibited that interaction of endurance training and low calorie diet decrese blood LDL-C (P=0.001), TG (P=0.006), TC (P=0.011) and homocysteine (P=0.001), whereas increased HDL-C (P=0.001) levels significantly. Conclusion: This study demonstrated that endurance training and low calorie diet interventions are effectiveness in reducing lipid profile and homocysteine levels among patients with NAFLD. However, combined interventions specifically improves NAFLD and has a better effect.
کلیدواژه‌ها
Non-Alcoholic fatty liver disease؛ Exercise؛ Caloric Restriction؛ Homocysteine
مراجع
  1. Katsiki N, Mikhailidis DP, Mantzoros CS. Non-alcoholic fatty liver disease and dyslipidemia: An update. Metabolism. 2016;65(8):1109–23.
  2. Romero-Gomez M, Zelber-Sagi S, Trenell M, Markisic M, Pavlovic AM, Pavlovic DM, et al. Treatment of NAFLD with diet, physical activity and exercise. Am J Gastroenterol. 2017;67(4):193–201.
  3. Lonardo A, Sookoian S, Pirola CJ, Targher G. Non-alcoholic fatty liver disease and risk of cardiovascular disease. Metabolism. 2016;65(8):1136–50.
  4. Zhang Q, Lu L. Review article Nonalcoholic Fatty Liver Disease : Dyslipidemia , Risk for Cardiovascular Complications , and Treatment Strategy. 2015;3:78–84.
  5. Azzam H, Malnick S. Non-alcoholic fatty liver disease - the heart of the matter. 2015;7(10):1369–76.
  6. Francque SM, van der Graaff D, Kwanten WJ. Non-alcoholic fatty liver disease and cardiovascular risk: Pathophysiological mechanisms and implications. Vol. 65, Journal of Hepatology. European Association for the Study of the Liver; 2016. p. 425–43.
  7. Boyacioglu M, Sekkin S, Kum C, Korkmaz D, Kiral F, Yalinkilinc HS, et al. The protective effects of vitamin C on the DNA damage, antioxidant defenses and aorta histopathology in chronic hyperhomocysteinemia induced rats. Exp Toxicol Pathol. 2014;66(9–10):407–13.
  8. Dai H, Wang W, Tang X, Chen R, Chen Z, Lu Y, et al. Association between homocysteine and non-alcoholic fatty liver disease in Chinese adults: a cross-sectional study. Nutr J. 2016;15(1):102.
  9. Deminice R, Ribeiro DF, Frajacomo FTT. The effects of acute exercise and exercise training on plasma homocysteine: A meta-analysis. PLoS One. 2016;11(3):1–17.
  10. Hallsworth K, Avery L, Trenell MI. Targeting lifestyle behavior change in adults with NAFLD during a 20-min consultation: summary of the dietary and exercise literature. Curr Gastroenterol Rep. 2016;18(3):11.
  11. Gondim OS, De Camargo VTN, Gutierrez FA, De Oliveira Martins PF, Passos MEP, Momesso CM, et al. Benefits of regular exercise on inflammatory and cardiovascular risk markers in normal weight, overweight and obese adults. PLoS One. 2015;10(10):1–14.
  12. Subasi SS, Gelecek N, Aksakoglu G, Ormen M. Effects of two different exercise trainings on plasma homocysteine levels and other cardiovascular disease risks. Turkish J Biochem. 2012;37(2):303–14.
  13. Lee J, Hong S, Shin Y. Effects of exercise training on stroke risk factors, homocysteine concentration, and cognitive function according the APOE genotype in stroke patients. J Exerc Rehabil. 2018;14(2):267–74.
  14. Habibian M, Monavri M. Comparison of Homocysteine and Heat Shock Protein 72 Responses Following Two Different Exercise Methods in Sedentary Women. Q Horiz Med Sci. 2017;23(2):123–8.
  15. Kotrlik J HC. Organizational research: Information technology, learning, and performance journal. 2001;19(1):43.
  16. Review T, LaBrecque DR, Abbas Z, Anania F, Ferenci P, Khan AG, et al. World Gastroenterology Organisation Global Guidelines: Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. J Clin Gastroenterol. 2014;48(6):467–73.
  17. Finkler E, Heymsfield SB, St-Onge MP. Rate of weight loss can be predicted by patient characteristics and intervention strategies. J Acad Nutr Diet. 2012;112(1):75–80.
  18. Rahman Soori, Servat Choopani, Falahian Nafiseh AR. Effect of Physical Activity on Serum Homocysteine Levels in Obese and Overweight Women. Q Horiz Med Sci. 2016;22(4):307–12.
  19. Markisic M, Pavlović AM, Pavlovic DM. The Impact of Homocysteine, Vitamin B12, and Vitamin D Levels on Functional Outcome after First-Ever Ischaemic Stroke. Biomed Res Int. 2017;2017.
  20. Joubert LM, Manore MM. Exercise , Nutrition , and Homocysteine. Int J Sport Nutr Exerc Metab. 2006;16(4):341–61.
  21. Swart KM, van Schoor NM, Heymans MW, Schaap LA, den Heijer M, Lips P.. Elevated homocysteine levels are associated with low muscle strength and functional limitations in older person. 2013;17(6).
  22. Kannan U, Vasudevan K, Balasubramaniam K, Yerrabelli D, Shanmugavel K, John NA. Effect of exercise intensity on lipid profile in sedentary obese adults. J Clin Diagnostic Res. 2014;8(7):8–11.
  23. Moradi aa, Mogharnasi M RE. Effects of 12 Weeks of Endurance Training on Soluble Intercellular Adhesion Molecule-1 and Lipid Profiles of Elderly Men. J Isfahan Med Sch. 1390;29(155):1426–34.
  24. De Sousa M V., Fukui R, Krustrup P, Pereira RMR, Silva PRS, Rodrigues AC, et al. Positive effects of football on fitness, lipid profile, and insulin resistance in Brazilian patients with type 2 diabetes. Scand J Med Sci Sport. 2014;24:57–65.
  25. Askari A, Askari B, Fallah Z, Sh K. Effect of eight weeks aerobic training on serum lipid and lipoprotein levels in women. 2012;14(1):26–32.
  26. Di Costanzo A, D’Erasmo L, Polimeni L, Baratta F, Coletta P, Di Martino M, et al. Non-alcoholic fatty liver disease and subclinical atherosclerosis: A comparison of metabolically- versus genetically-driven excess fat hepatic storage. Atherosclerosis. 2017;257(1):232–9.
  27. Nayebifar SH, Afzalpour ME, Saghebjou M HM. The effects of resistance training and aerobic exercise on intercellular adhesion molecules and lipid profile in overweight women. Sport Biomotor Sci. 1389;4:77–87.
  28. Hashida R, Kawaguchi T, Bekki M, Omoto M, Matsuse H, Nago T, et al. Aerobic vs. resistance exercise in non-alcoholic fatty liver disease: A systematic review. J Hepatol. 2017;66(1):142–52.
  29. Zar A, Hosseini SA, Homaion A. Effect of Eight-Week Aquagymnastic Training on Liver Enzymes and Lipid Profile of Middle-Aged Women. Qom Univ Med Sci. 2016; 10(7):29-37.
  30. Guo R, Liong E, So K, Fung M, Tipoe G. Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease. Hepatobiliary Pancreat Dis Int. 2015;14(2):139–44.
آمار
تعداد مشاهده مقاله: 673
تعداد دریافت فایل اصل مقاله: 402


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب