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Comparison of Abnormal Cervical Cytology from HIV Positive Women, Female Sex Workers and General Population | ||
International Journal of Community Based Nursing & Midwifery | ||
مقاله 1، دوره 3، شماره 2 - شماره پیاپی 10، تیر 2015، صفحه 76-83 اصل مقاله (294.98 K) | ||
نوع مقاله: Original article | ||
نویسندگان | ||
Homeira Vafaei1؛ Nasrin Asadi2؛ Leila Foroughinia2؛ Alireza Salehi* 3؛ Safieh Kuhnavard2؛ Mojgan Akbarzadeh4؛ Hamid Reza Ravanbod5؛ Ferdos Mohamadalian6؛ Maryam Kasraeian2 | ||
1Maternal Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
2Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, Iran | ||
3Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran | ||
4Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran | ||
5Biomedical Science Centre, Charles Sturt University, Melbourne, Australia | ||
6Nursing School and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran | ||
چکیده | ||
Background: Sex workers and HIV seropositive women are at high risk of abnormal cervical cytology. The objective of this study was to compare the cervical cytology among three groups of women: active sex workers, HIV-infected women, and general population in Iran.Methods: This was a cross-sectional study performed in Hazrat Zeinab, Lavan clinics and drop in center (DIC) in Shiraz, Iran. This study was performed from October 2009 to October 2011. A total of 266 patients were assigned into three groups: sex-workers (85), HIV positive patients (100), and general population (81). Pap smear was performed for all participants from the exocervix and endocervix, using a plastic Ayres’s spatula and cytobrush. The samples were sent to a pathology center, using a liquid-based media. Results: The risk of cervical infection in sex workers and HIV positive women was greater than the general population (OR=5.47, 95% confidence interval [CI]:2.24, 13.40), (OR=3.71, 95% CI:1.52, 9.09), respectively. The frequency of abnormal cervical cytology in the HIV positive and sex worker groups was higher than the general population (OR=6. 76, 95% CI:2.25, 20.32), (OR=3. 80, 95% CI:1.19, 12.07), respectively. Low-grade squamous intraepithelial lesion (LSIL) and high-grade squamous intraepithelial lesion (HSIL) were associated with CD4 cell count<200Í106/L, P=0.021 and P<0.001, respectively.Conclusion: Vaginal infections were seen more often in the sex worker group, and abnormal cervical cytology was greater in the HIV positive group. | ||
کلیدواژهها | ||
HIV/AIDs؛ Sex Worker؛ Pap smear؛ Iran | ||
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