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Barzin, Zahra, Sadjjadi, Seyed Mahmoud, Panjehshahin, Mohammad Reza. (1397). Protoscolicidal Effects of the Garlic Chloroformic Extract on the Protoscolices of Hydatid Cyst at a Short Exposure Time, up to Five Minutes. سامانه مدیریت نشریات علمی, 44(1), 28-34. doi: 10.30476/ijms.2019.40620
Zahra Barzin; Seyed Mahmoud Sadjjadi; Mohammad Reza Panjehshahin. "Protoscolicidal Effects of the Garlic Chloroformic Extract on the Protoscolices of Hydatid Cyst at a Short Exposure Time, up to Five Minutes". سامانه مدیریت نشریات علمی, 44, 1, 1397, 28-34. doi: 10.30476/ijms.2019.40620
Barzin, Zahra, Sadjjadi, Seyed Mahmoud, Panjehshahin, Mohammad Reza. (1397). 'Protoscolicidal Effects of the Garlic Chloroformic Extract on the Protoscolices of Hydatid Cyst at a Short Exposure Time, up to Five Minutes', سامانه مدیریت نشریات علمی, 44(1), pp. 28-34. doi: 10.30476/ijms.2019.40620
Barzin, Zahra, Sadjjadi, Seyed Mahmoud, Panjehshahin, Mohammad Reza. Protoscolicidal Effects of the Garlic Chloroformic Extract on the Protoscolices of Hydatid Cyst at a Short Exposure Time, up to Five Minutes. سامانه مدیریت نشریات علمی, 1397; 44(1): 28-34. doi: 10.30476/ijms.2019.40620

Protoscolicidal Effects of the Garlic Chloroformic Extract on the Protoscolices of Hydatid Cyst at a Short Exposure Time, up to Five Minutes

Iranian Journal of Medical Sciences
مقاله 4، دوره 44، شماره 1، فروردین 2019، صفحه 28-34    اصل مقاله (376.51 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2019.40620
نویسندگان
Zahra Barzin1؛ Seyed Mahmoud Sadjjadi* 2؛ Mohammad Reza Panjehshahin3
1Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; and Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3Department of Pharmacology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: The treatment of choice for hydatidosis as an important zoonotic disease is surgery. Different agents are injected into the cyst to prevent secondary hydatidosis. To avoid the side effects of such protoscolicidal agents, considering the high protoscolicidal effects of the garlic extract, we conducted the present study on protoscolices in limited applicable times and compared the extract with some chemical agents. Methods: Sheep’s liver and lung cysts were collected. Ninety tubes were selected and divided into 3 sets (for different exposure times), each one comprising 5 groups of 6 tubes. Each tube contained 3000–4000 protoscolices. The groups were 0.5% cetrimide (as positive control), 20% hypertonic sodium chloride, 0.5% silver nitrate, 0.9% normal saline (as negative control), and the garlic chloroformic extract (200 mg/mL). The viability of the protoscolices was assessed using 0.1% eosin. The ANOVA and LSD were used to compare the mean viability of the protoscolices after exposure to the different agents at different times and concentrations. The data were analyzed using SPSS software, version 17. A P
کلیدواژه‌ها
Echinococcosis؛ Garlic؛ In Vitro techniques
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