LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,149
تعداد مقالات10,518
تعداد مشاهده مقاله45,416,352
تعداد دریافت فایل اصل مقاله11,292,301
Bagheri, Hamed, Rezapour, Saeed, Najafi, Masoud, Motevaseli, Elahe, Shekarchi, Babak, Cheki, Mohsen, Mozdarani, Hossein. (1397). Protection Against Radiation-Induced Micronuclei in Rat Bone Marrow Erythrocytes by Curcumin and Selenium L-Methionine. سامانه مدیریت نشریات علمی, 43(6), 645-652. doi: 10.30476/ijms.2018.40588
Hamed Bagheri; Saeed Rezapour; Masoud Najafi; Elahe Motevaseli; Babak Shekarchi; Mohsen Cheki; Hossein Mozdarani. "Protection Against Radiation-Induced Micronuclei in Rat Bone Marrow Erythrocytes by Curcumin and Selenium L-Methionine". سامانه مدیریت نشریات علمی, 43, 6, 1397, 645-652. doi: 10.30476/ijms.2018.40588
Bagheri, Hamed, Rezapour, Saeed, Najafi, Masoud, Motevaseli, Elahe, Shekarchi, Babak, Cheki, Mohsen, Mozdarani, Hossein. (1397). 'Protection Against Radiation-Induced Micronuclei in Rat Bone Marrow Erythrocytes by Curcumin and Selenium L-Methionine', سامانه مدیریت نشریات علمی, 43(6), pp. 645-652. doi: 10.30476/ijms.2018.40588
Bagheri, Hamed, Rezapour, Saeed, Najafi, Masoud, Motevaseli, Elahe, Shekarchi, Babak, Cheki, Mohsen, Mozdarani, Hossein. Protection Against Radiation-Induced Micronuclei in Rat Bone Marrow Erythrocytes by Curcumin and Selenium L-Methionine. سامانه مدیریت نشریات علمی, 1397; 43(6): 645-652. doi: 10.30476/ijms.2018.40588

Protection Against Radiation-Induced Micronuclei in Rat Bone Marrow Erythrocytes by Curcumin and Selenium L-Methionine

Iranian Journal of Medical Sciences
مقاله 9، دوره 43، شماره 6، بهمن 2018، صفحه 645-652    اصل مقاله (389.83 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2018.40588
نویسندگان
Hamed Bagheri1؛ Saeed Rezapour2؛ Masoud Najafi3؛ Elahe Motevaseli4؛ Babak Shekarchi1؛ Mohsen Cheki5؛ Hossein Mozdarani* 6
1Radiation and Wave Research Center, Aja University of Medical Sciences, Tehran, Iran
2Department of Radiology, Allied Medical School, Tehran University of Medical Sciences, Tehran, Iran
3Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
5Department of Radiology, Faculty of Paramedical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
6Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
چکیده
Background: The search for potent radioprotective agents for the amelioration of radiation side effect is an important aim in radiobiology. The present study aimed to evaluate the effects of curcumin and seleno-L-methionine against radiation-induced micronucleus formation in rat bone marrow.Methods: In total, 40 male rats were divided into 8 groups (n=5 each), including control, curcumin or seleno-L-methionine treated alone or in combination, 2 Gy irradiation, irradiation of treated groups with curcumin or seleno-L-methionine or their combination. Curcumin was administrated orally and seleno-L-methionine was injected intraperitoneally 24 hours before irradiation. The frequency of micronucleated normochromatic erythrocytes (MnNCEs) and micronucleated polychromatic erythrocytes (MnPCEs) was scored in 5,000 polychromatic erythrocytes (PCEs) and the cell proliferation ratio [(PCE/(PCE+NCE); NCE=normochromatic erythrocytes] was calculated for each treatment group. Data were analyzed by the SPSS software version 16.0 and P
کلیدواژه‌ها
Radiation protection؛ Curcumin؛ Seleno-L-methionine selenoxide؛ Micronuclei؛ Gamma rays
آمار
تعداد مشاهده مقاله: 7,769
تعداد دریافت فایل اصل مقاله: 1,969


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب