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Bagheri, Sina, Shahbazi, Shahrbanoo, Shafa, Masih, Borhani-Haghighi, Afshin, Kiani, Mahsa, Sagheb, Mohammad Mahdi. (1397). The Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial. سامانه مدیریت نشریات علمی, 43(6), 587-595. doi: 10.30476/ijms.2018.40581
Sina Bagheri; Shahrbanoo Shahbazi; Masih Shafa; Afshin Borhani-Haghighi; Mahsa Kiani; Mohammad Mahdi Sagheb. "The Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial". سامانه مدیریت نشریات علمی, 43, 6, 1397, 587-595. doi: 10.30476/ijms.2018.40581
Bagheri, Sina, Shahbazi, Shahrbanoo, Shafa, Masih, Borhani-Haghighi, Afshin, Kiani, Mahsa, Sagheb, Mohammad Mahdi. (1397). 'The Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial', سامانه مدیریت نشریات علمی, 43(6), pp. 587-595. doi: 10.30476/ijms.2018.40581
Bagheri, Sina, Shahbazi, Shahrbanoo, Shafa, Masih, Borhani-Haghighi, Afshin, Kiani, Mahsa, Sagheb, Mohammad Mahdi. The Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial. سامانه مدیریت نشریات علمی, 1397; 43(6): 587-595. doi: 10.30476/ijms.2018.40581

The Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial

Iranian Journal of Medical Sciences
مقاله 3، دوره 43، شماره 6، بهمن 2018، صفحه 587-595    اصل مقاله (378.92 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2018.40581
نویسندگان
Sina Bagheri1؛ Shahrbanoo Shahbazi* 2؛ Masih Shafa3؛ Afshin Borhani-Haghighi4؛ Mahsa Kiani1؛ Mohammad Mahdi Sagheb1
1Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3Department of Cardiac Surgery, Shiraz University of Medical Sciences, Shiraz, Ira
4Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Remote ischemic preconditioning (RIPC) protects other organs from subsequent lethal ischemic injury, but uncertainty remains. We investigated if RIPC could prevent acute kidney injury (AKI) in patients undergoing coronary artery bypass graft (CABG) surgery.Methods: This parallel-group, double-blind, randomized, controlled trial was done on adults undergoing elective or urgent on-pump CABG surgery from 2013 to 2017 in Shiraz, Iran. Patients were allocated to RIPC or control groups through permuted blocking. The patients in the RIPC group received three cycles of 5 min ischemia and 5 min reperfusion in the upper arm after induction of anesthesia. We placed an uninflated cuff on the arm for 30 min in the control group. The study primary endpoint was an incidence of AKI. Secondary endpoints included short-term clinical outcomes. We compared categorical and continuous variables using Pearson χ2 and unpaired t tests, respectively. P
کلیدواژه‌ها
schemic preconditioning؛ Reperfusion injury؛ Acute kidney injury؛ Coronary artery bypass
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