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Maitra, Aditi, Bhattacharyya, Shashwat, Paik, Sabyasachi, Pathak, Prerna, Tripathi, Santanu. (1396). A Rare Case of Fixed Drug Eruption due to Ondansetron. سامانه مدیریت نشریات علمی, 42(5), 497-500.
Aditi Maitra; Shashwat Bhattacharyya; Sabyasachi Paik; Prerna Pathak; Santanu Kumar Tripathi. "A Rare Case of Fixed Drug Eruption due to Ondansetron". سامانه مدیریت نشریات علمی, 42, 5, 1396, 497-500.
Maitra, Aditi, Bhattacharyya, Shashwat, Paik, Sabyasachi, Pathak, Prerna, Tripathi, Santanu. (1396). 'A Rare Case of Fixed Drug Eruption due to Ondansetron', سامانه مدیریت نشریات علمی, 42(5), pp. 497-500.
Maitra, Aditi, Bhattacharyya, Shashwat, Paik, Sabyasachi, Pathak, Prerna, Tripathi, Santanu. A Rare Case of Fixed Drug Eruption due to Ondansetron. سامانه مدیریت نشریات علمی, 1396; 42(5): 497-500.

A Rare Case of Fixed Drug Eruption due to Ondansetron

Iranian Journal of Medical Sciences
مقاله 11، دوره 42، شماره 5، آذر 2017، صفحه 497-500    اصل مقاله (349.99 K)
نوع مقاله: Case Report(s)
نویسندگان
Aditi Maitra* 1؛ Shashwat Bhattacharyya2؛ Sabyasachi Paik1؛ Prerna Pathak3؛ Santanu Kumar Tripathi1
1Department of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, India;
2Department of Ophthalmology, Calcutta National Medical College, Kolkata, India
3Department of Dermatology and Venereology, Calcutta School of Tropical Medicine, Kolkata, India
چکیده
AbstractFixed drug eruption (FDE) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. FDE is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. A 27-year-old woman presented with multiple dark patches over her eyelids, mouth, lips, and shoulders of 1 week’s duration. These lesions followed multiple erythematous plaques over the same areas which appeared within 4 hours of the intake of an ondansetron tablet, 12 days previously. The case was diagnosed as post-inflammatory hyperpigmentation following ondansetron-induced FDE. There was an identical episode 1 year earlier due to the intake of the same drug. The causality assessment pointed toward a probable/likely association as per the Naranjo algorithm and the WHO–UMC scale. There have been only a few cases of FDE due to ondansetron in the reported literature.
کلیدواژه‌ها
Ondansetron؛ Hyperpigmentation؛ Fixed drug eruption؛ 5HT3 receptor antagonists
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