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Relationship between Body Mass Index, Waist-to-Hip Ratio, and Serum Lipid Concentrations and Thyroid-Stimulating Hormone in the Euthyroid Adult Population | ||
Iranian Journal of Medical Sciences | ||
مقاله 10، دوره 42، شماره 3، مرداد 2017، صفحه 301-305 اصل مقاله (226.49 K) | ||
نوع مقاله: Brief Report(s) | ||
نویسندگان | ||
Ali Reza Rahbar* 1؛ Mohamadreza Kalantarhormozi2؛ Fatemeh Izadi1؛ Elham Arkia1؛ Marzie Rashidi1؛ Fatemeh Pourbehi1؛ Farzaneh Daneshifard1؛ Amin Rahbar2 | ||
1Persian Gulf Tropical Medicine Research Center, Department of Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran | ||
2Persian Gulf Tropical Medicine Research Center, Department of Endocrinology, Bushehr University of Medical Sciences, Bushehr, Iran | ||
چکیده | ||
Background: The aim of this cross-sectional study was to investigate the relationship between body mass index (BMI), waist-to-hip ratio, and lipid parameters and serum thyroid-stimulating hormone (TSH) levels in healthy euthyroid individuals.Methods: This cross-sectional study was conducted between June 1st and July 20th, 2013, at Bushehr University of Medical Sciences. One hundred forty euthyroid individuals were divided into 2 groups: a high-TSH group (TSH between 2.0 and 5.5 mIU/L, n=67) and a low-TSH group (TSH between 0.3 and 2.0 mIU/L, n=73). After overnight fast, total cholesterol, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), TSH, thyroxine (T4), and triiodothyronine (T3) were measured. Height and weight were measured with a stadiometer, and BMI was calculated as weight in kilograms divided by the square of height in meters. Waist-to-hip ratio was determined as waist circumference divided by hip circumference. The simple independent t-test and a general linear model were used for statistical analysis. All statistical analyses were done using the SPSS, version 15, statistical software package.Results: BMI and LDL-C were significantly higher in the high-TSH group than in the low-TSH group after adjustment for age, sex, calorie intake, total fat and carbohydrate intakes, and physical activity. No significant differences were found between the groups in TG, cholesterol, and HDL-C. The association between TSH levels andT4 was significant.Conclusion: Individuals with TSH levels at the upper limit of normality might be at risk of hypercholesterolemia and obesity. | ||
کلیدواژهها | ||
Dyslipidemias؛ Obesity؛ Thyrotropin | ||
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