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The Effect of Bone Marrow Graft on Bone Healing: A Radiological and Biomechanical Study | ||
| Iranian Journal of Medical Sciences | ||
| مقاله 5، دوره 27، شماره 2، بهمن 2002، صفحه 63-66 اصل مقاله (42.43 K) | ||
| نوع مقاله: Original Article(s) | ||
| نویسندگان | ||
| M.J. Emami* ؛ A. Oryan؛ H. Saeidinasab؛ A. Meimandi Parizi | ||
| چکیده | ||
| Background: There are multiple methods for acceleration of bone healing. Bone marrow has been shown to contain osteoprogenitor cells. Objective: To determine the effect of percutaneous bone marrow injection on bone healing. Methods: 15 mature, 2-kg-weighing white New Zealand rabbits from both sexes were randomized into 3 groups: Group I: Only osteotomy of right radius was performed and a 5 mm bony defect was made. Group II: Same as group I, with the defect filled by bone-graft, taken from the iliac crest. Group III: Same as group I plus percutaneous bone marrow injection 5 days after the operation. 45 days post-operation, the rabbits were sacrificed. The radii of both forelimbs were isolated and tested by tensile testing machine. Results: There was a significant difference between groups I and III (p<0.001) for toleration of maximum load and bending stiffness. No significant difference was observed between groups II and III for these parameters. Conclusion: Bone marrow injection has an effect on bone healing comparable to bone grafting. This technique is non-invasive and simple without any significant complication. | ||
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