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Nematbakhsh, M., Habibi, H.R., Soltani, N., Hayatdavoodi, P., Naji, H., Borjian, L.. (1394). Gender Difference in Endothelial Permeability of Aorta in Rabbits Consuming Normal or High-Cholesterol Diets. سامانه مدیریت نشریات علمی, 28(4), 200-202.
M. Nematbakhsh; H.R. Habibi; N. Soltani; P. Hayatdavoodi; H. Naji; L. Borjian. "Gender Difference in Endothelial Permeability of Aorta in Rabbits Consuming Normal or High-Cholesterol Diets". سامانه مدیریت نشریات علمی, 28, 4, 1394, 200-202.
Nematbakhsh, M., Habibi, H.R., Soltani, N., Hayatdavoodi, P., Naji, H., Borjian, L.. (1394). 'Gender Difference in Endothelial Permeability of Aorta in Rabbits Consuming Normal or High-Cholesterol Diets', سامانه مدیریت نشریات علمی, 28(4), pp. 200-202.
Nematbakhsh, M., Habibi, H.R., Soltani, N., Hayatdavoodi, P., Naji, H., Borjian, L.. Gender Difference in Endothelial Permeability of Aorta in Rabbits Consuming Normal or High-Cholesterol Diets. سامانه مدیریت نشریات علمی, 1394; 28(4): 200-202.

Gender Difference in Endothelial Permeability of Aorta in Rabbits Consuming Normal or High-Cholesterol Diets

Iranian Journal of Medical Sciences
مقاله 11، دوره 28، شماره 4، بهمن 2003، صفحه 200-202    اصل مقاله (42.02 K)
نوع مقاله: Brief Report(s)
نویسندگان
M. Nematbakhsh* ؛ H.R. Habibi؛ N. Soltani؛ P. Hayatdavoodi؛ H. Naji؛ L. Borjian
Department of Physiology, Isfahan University of Medical Sci-ences Isfahan, Iran.
چکیده
The endothelial permeability of aorta (EPA) is influenced by atherosclerosis.  Whether the physiological difference in EPA is a sex-dependent phenomenon remains to be determined.  The objective of this study was to determine the EPA difference between male and female rabbits.  An experimental model was designed to obtain 4 groups of animals.  The ovariectomized rabbits were fed with normal (group I) and 1% cholesterol-rich diets (group III).  The male rabbits also received normal (group II) and cholesterol-rich diets (group IV).  After 5 wks, the EPA was measured by Evan Blue (EB) dye uptake method.  The EB uptake was significantly (p<0.05) lower in females, regardless of the diet they used.  In groups I to IV, the mean±SD EB uptake was 4.83±2.06, 15.15±2.91, 7.01±2.40, and 20.58±3.62 mg/g weight of aorta, respectively.  The lower EPA in females may play a role in reducing the risk of development of atherosclerosis. 
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